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Our <span class="xdx_phnt_RGlzY2xvc3VyZSAtIEluc2lkZXIgVHJhZGluZyBQb2xpY2llcyBhbmQgUHJvY2VkdXJlcwA_" id="xdx_906_eecd--InsiderTrdPoliciesProcAdoptedFlag_dbF_c20250101__20251231_z7bOzRrJTzJ2">Insider Trading Policy</span> provides that no employee, officer or director may acquire, sell or trade in any interest or position relating to the future price of Company securities, such as a put option, a call option or a short sale (including a short sale “against the box”), or engage in hedging transactions (including “cashless collars”). false <table cellpadding="0" cellspacing="0" id="xdx_88B_eecd--PvpTableTextBlock_zzFE6T3WGL3" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Pay vs Performance Disclosure"> <tr style="vertical-align: bottom"> <td style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><b>Year</b></td><td style="text-align: center; font-weight: bold; padding-bottom: 1pt"><b> </b></td> <td colspan="2" id="xdx_485_eecd--PeoTotalCompAmt_hecd--IndividualAxis__custom--DatukDrDorisWongSingEeMember_zwenHNBQqtI6" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Summary Compensation Table Total for CEO 1 <span><sup id="xdx_F53_zvhjPoYR61o3">(1) (2)</sup></span></b></span></td><td style="text-align: center; padding-bottom: 1pt; font-weight: bold"><b> </b></td><td style="text-align: center; font-weight: bold; padding-bottom: 1pt"><b> </b></td> <td colspan="2" id="xdx_486_eecd--PeoActuallyPaidCompAmt_hecd--IndividualAxis__custom--DatukDrDorisWongSingEeMember_zS0a0urO2nR5" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Compensation Actually Paid to CEO 1<span><sup id="xdx_F54_ztABduOYgFw">(1) (3)</sup></span></b></span></td><td style="text-align: center; padding-bottom: 1pt; font-weight: bold"><b> </b></td> <td> </td><td colspan="2" id="xdx_485_eecd--PeoTotalCompAmt_hecd--IndividualAxis__custom--MrDavidLazarMember_z4DaYxxwoq3e" style="border-bottom: Black 1pt solid; text-align: center; font-weight: bold"><p style="text-align: center; margin-top: 0; margin-bottom: 0"><b>Summary Compensation Table Total for CEO 2 <sup id="xdx_F55_zmsF1amWKlf9">(1) (2)</sup></b></p> </td> <td style="padding-bottom: 1pt; text-align: center"><b> </b></td> <td style="text-align: center; padding-bottom: 1pt"> </td> <td colspan="2" id="xdx_480_eecd--PeoActuallyPaidCompAmt_hecd--IndividualAxis__custom--MrDavidLazarMember_zgSosQndIpc5" style="border-bottom: Black 1pt solid; text-align: center"><p style="text-align: center; margin-top: 0; margin-bottom: 0"><b>Compensation Actually Paid to CEO 2 <sup id="xdx_F5A_zbzrYIC4kuBl">(1) (3)</sup></b></p> </td> <td style="padding-bottom: 1pt; text-align: center"><b> </b></td> <td style="text-align: center; padding-bottom: 1pt"> </td> <td colspan="2" id="xdx_482_eecd--PeoTotalCompAmt_hecd--IndividualAxis__custom--MrSpiroRombotisMember_z0JTe5Ndzj37" style="border-bottom: Black 1pt solid; text-align: center"><p style="text-align: center; margin-top: 0; margin-bottom: 0"><b>Summary Compensation Table Total for CEO 3 <sup id="xdx_F5E_zbnQc3uLLsnf">(1) (2)</sup></b></p> </td> <td style="text-align: center; padding-bottom: 1pt"> </td> <td> </td> <td colspan="2" id="xdx_483_eecd--PeoActuallyPaidCompAmt_hecd--IndividualAxis__custom--MrSpiroRombotisMember_zIehHVL220ce" style="border-bottom: Black 1pt solid; text-align: center"><p style="text-align: center; margin-top: 0; margin-bottom: 0"><b>Compensation Actually Paid to CEO 3 <sup id="xdx_F51_zAM7ZFvL4zf8">(1) (3)</sup></b></p> </td> <td style="padding-bottom: 1pt; text-align: center"><b> </b></td> <td> </td> <td colspan="2" id="xdx_48B_eecd--NonPeoNeoAvgTotalCompAmt_z8WpI4v7S8U7" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Aggregate Summary Compensation Table Total for Non-CEO NEOs <span id="xdx_F5C_zEd1tTaKbSlj">^{(1) (2)}</span></b></span><b> <span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"> </span></b></td><td style="text-align: center; padding-bottom: 1pt; font-weight: bold"><b> </b></td><td style="text-align: center; font-weight: bold; padding-bottom: 1pt"><b> </b></td> <td colspan="2" id="xdx_487_eecd--NonPeoNeoAvgCompActuallyPaidAmt_zzbLTN4hs7bi" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Aggregate Compensation Actually Paid to Non-CEO NEOs<span id="xdx_F5C_zyRiTz1XxiYf">^{(1) (3)}</span></b></span></td><td style="text-align: center; padding-bottom: 1pt; font-weight: bold"><b> </b></td><td style="text-align: center; font-weight: bold; padding-bottom: 1pt"><b> </b></td> <td colspan="2" id="xdx_483_eecd--TotalShareholderRtnAmt_pp2d_zWOJnEDg4dPe" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Value of initial fixed $100 investment based on total shareholder return (TSR) <span id="xdx_F52_zZoKdNLT5Foa">⁽⁴⁾</span></b></span><b> <span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"> </span></b></td><td style="text-align: center; padding-bottom: 1pt; font-weight: bold"><b> </b></td><td style="text-align: center; font-weight: bold; padding-bottom: 1pt"><b> </b></td> <td colspan="2" id="xdx_488_eus-gaap--NetIncomeLoss_iN_pn3n3_di_zR8MOfNCHDC4" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Net Loss<br/> (in thousands) <span id="xdx_F5B_ztqCXeKHhCzb">⁽⁵⁾</span></b></span></td><td style="text-align: center; padding-bottom: 1pt; font-weight: bold"><b> </b></td></tr> <tr id="xdx_414_20250101__20251231_zNYL1gr7kFVi" style="vertical-align: bottom; background-color: rgb(204,238,255)"> <td style="width: 7%; font-weight: bold; text-align: center">2025</td><td style="width: 1%"> </td> <td style="width: 1%; text-align: left">$</td><td style="width: 6%; text-align: right">470,785</td><td style="width: 1%; text-align: left"> </td><td style="width: 1%"> </td> <td style="width: 1%; text-align: left">$</td><td style="width: 6%; text-align: right">50,536</td><td style="width: 1%; text-align: left"> </td> <td style="width: 1%"> </td><td style="width: 1%">$</td> <td style="text-align: right; width: 6%">66,250</td> <td style="width: 1%"> </td> <td style="width: 1%"> </td> <td style="width: 1%">$</td> <td style="text-align: right; width: 6%">66,250</td> <td style="width: 1%"> </td> <td style="width: 1%"> </td> <td style="width: 1%">$</td> <td style="text-align: right; width: 6%">847,436</td> <td style="width: 1%"> </td> <td style="width: 1%"> </td> <td style="width: 1%">$</td> <td style="text-align: right; width: 6%">847,436</td> <td style="width: 1%"> </td> <td style="width: 1%"> </td> <td style="width: 1%; text-align: left">$</td><td style="width: 6%; text-align: right">784,968</td><td style="width: 1%; text-align: left"> </td><td style="width: 1%"> </td> <td style="width: 1%; text-align: left">$</td><td style="width: 7%; text-align: right">504,968</td><td style="width: 1%; text-align: left"> </td><td style="width: 1%"> </td> <td style="width: 1%; text-align: left">$</td><td style="width: 7%; text-align: right">0.06</td><td style="width: 1%; text-align: left"> </td><td style="width: 1%"> </td> <td style="width: 1%; text-align: left">$</td><td style="width: 7%; text-align: right">(2,998</td><td style="width: 1%; text-align: left">)</td></tr> <tr id="xdx_41D_20240101__20241231_zXlUhGdpvqSh" style="vertical-align: bottom; background-color: White"> <td style="font-weight: bold; text-align: center">2024</td><td> </td> <td style="text-align: left">$</td><td style="text-align: right"><span style="-sec-ix-hidden: xdx2ixbrl0027">-</span></td><td style="text-align: left"> </td><td> </td> <td style="text-align: left">$</td><td style="text-align: right"><span style="-sec-ix-hidden: xdx2ixbrl0028">-</span></td><td style="text-align: left"> </td> <td> </td><td>$</td> <td style="text-align: right"><span style="-sec-ix-hidden: xdx2ixbrl0029">-</span></td> <td> </td> <td> </td> <td>$</td> <td style="text-align: right"><span style="-sec-ix-hidden: xdx2ixbrl0030">-</span></td> <td> </td> <td> </td> <td>$</td> <td style="text-align: right">585,000</td> <td> </td> <td> </td> <td>$</td> <td style="text-align: right">547,706</td> <td> </td> <td> </td> <td style="text-align: left">$</td><td style="text-align: right">363,988</td><td style="text-align: left"> </td><td> </td> <td style="text-align: left">$</td><td style="text-align: right">342,889</td><td style="text-align: left"> </td><td> </td> <td style="text-align: left">$</td><td style="text-align: right">3.76</td><td style="text-align: left"> </td><td> </td> <td style="text-align: left">$</td><td style="text-align: right">(11,212</td><td style="text-align: left">)</td></tr> <tr id="xdx_41D_20230101__20231231_zCKcQIGkX07g" style="vertical-align: bottom; background-color: rgb(204,238,255)"> <td style="font-weight: bold; text-align: center">2023</td><td> </td> <td style="text-align: left">$</td><td style="text-align: right"><span style="-sec-ix-hidden: xdx2ixbrl0037">-</span></td><td style="text-align: left"> </td><td> </td> <td style="text-align: left">$</td><td style="text-align: right"><span style="-sec-ix-hidden: xdx2ixbrl0038">-</span></td><td style="text-align: left"> </td> <td> </td><td>$</td> <td style="text-align: right"><span style="-sec-ix-hidden: xdx2ixbrl0039">-</span></td> <td> </td> <td> </td> <td>$</td> <td style="text-align: right"><span style="-sec-ix-hidden: xdx2ixbrl0040">-</span></td> <td> </td> <td> </td> <td>$</td> <td style="text-align: right">661,049</td> <td> </td> <td> </td> <td>$</td> <td style="text-align: right">65,807</td> <td> </td> <td> </td> <td style="text-align: left">$</td><td style="text-align: right">833,233</td><td style="text-align: left"> </td><td> </td> <td style="text-align: left">$</td><td style="text-align: right">172,676</td><td style="text-align: left"> </td><td> </td> <td style="text-align: left">$</td><td style="text-align: right">26.69</td><td style="text-align: left"> </td><td> </td> <td style="text-align: left">$</td><td style="text-align: right">(22,555</td><td style="text-align: left">)</td></tr> </table> 470785 50536 66250 66250 847436 847436 784968 504968 0.06 2998000 585000 547706 363988 342889 3.76 11212000 661049 65807 833233 172676 26.69 22555000 <p id="xdx_890_eecd--NamedExecutiveOfficersFnTextBlock_dU_zQdenEaEXAe3" style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"></p> <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"> </span></p> <table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse"> <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top"> <td style="font: 10pt Times New Roman, Times, Serif; width: 0.25in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</span></td> <td style="font: 10pt Times New Roman, Times, Serif"><p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">For the year 2025, CEO 1 was <span id="xdx_901_eecd--PeoName_c20250101__20251231__ecd--IndividualAxis__custom--PEO1Member_zCjKhtdyl7sj">Datuk Dr. Doris Wong Sing Ee</span>, CEO 2 was <span id="xdx_904_eecd--PeoName_c20250101__20251231__ecd--IndividualAxis__custom--PEO2Member_zR4jr1Rdwpcb">Mr. David Lazar</span> and CEO 3 was <span id="xdx_902_eecd--PeoName_c20250101__20251231__ecd--IndividualAxis__custom--PEO3Member_zGkG3eVdsH8g">Mr. Spiro Rombotis</span>.</span> <span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">For years 2024 and 2023, the CEO was Spiro Rombotis. The Non-CEO named executive officers (the “<b>NEO</b>s”) were Mr. Kiu Cu Seng for 2025, Mr. Paul McBarron for all years and Mark Kirschbaum, MD for 2024 and 2023.</span></p> <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p></td></tr> </table> Datuk Dr. Doris Wong Sing Ee Mr. David Lazar Mr. Spiro Rombotis <p id="xdx_891_eecd--AdjToPeoCompFnTextBlock_dU_zmKFCoH0MFC4" style="margin: 0"> </p> <table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse"> <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top"> <td style="font: 10pt Times New Roman, Times, Serif; width: 0.25in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(5)</span></td> <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The dollar amounts reported represent the amount of net loss reflected in the Company’s audited financial statements for the applicable year.</span></td></tr> </table> <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"> </span></p> <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0"> </p> <table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%"> <tr style="vertical-align: bottom"> <td style="text-align: center"> </td><td style="font-weight: bold; padding-bottom: 1pt"> </td> <td colspan="14" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center">Fiscal Year 2025</td><td style="padding-bottom: 1pt; font-weight: bold"> </td><td style="font-weight: bold; padding-bottom: 1pt"> </td> <td colspan="6" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center">Fiscal Year 2024</td><td style="padding-bottom: 1pt; font-weight: bold"> </td><td style="font-weight: bold; padding-bottom: 1pt"> </td> <td colspan="6" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center">Fiscal Year 2023</td><td style="padding-bottom: 1pt; font-weight: bold"> </td></tr> <tr style="vertical-align: bottom"> <td style="padding-bottom: 1pt; text-align: center"><b> </b></td><td style="text-align: center; font-weight: bold; padding-bottom: 1pt"><b> </b></td> <td colspan="2" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><b>CEO 1</b></td><td style="text-align: center; padding-bottom: 1pt; font-weight: bold"><b> </b></td><td style="text-align: center; font-weight: bold; padding-bottom: 1pt"><b> </b></td> <td colspan="2" style="border-bottom: Black 1pt solid; text-align: center"><b>CEO 2</b></td> <td style="padding-bottom: 1pt; text-align: center"><b> </b></td> <td style="padding-bottom: 1pt; text-align: center"><b> </b></td> <td colspan="2" style="border-bottom: Black 1pt solid; text-align: center"><b>CEO 3</b></td> <td style="padding-bottom: 1pt; text-align: center"><b> </b></td> <td style="padding-bottom: 1pt; text-align: center"><b> </b></td> <td colspan="2" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><b>NON- CEO NEO’s</b></td><td style="text-align: center; padding-bottom: 1pt; font-weight: bold"><b> </b></td><td style="text-align: center; font-weight: bold; padding-bottom: 1pt"><b> </b></td> <td colspan="2" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><b>CEO</b></td><td style="text-align: center; padding-bottom: 1pt; font-weight: bold"><b> </b></td><td style="text-align: center; font-weight: bold; padding-bottom: 1pt"><b> </b></td> <td colspan="2" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><b>NON- CEO NEO’s</b></td><td style="text-align: center; padding-bottom: 1pt; font-weight: bold"><b> </b></td><td style="text-align: center; font-weight: bold; padding-bottom: 1pt"><b> </b></td> <td colspan="2" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><b>CEO</b></td><td style="text-align: center; padding-bottom: 1pt; font-weight: bold"><b> </b></td><td style="text-align: center; font-weight: bold; padding-bottom: 1pt"><b> </b></td> <td colspan="2" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><b>NON- CEO NEO’s</b></td><td style="text-align: center; padding-bottom: 1pt; font-weight: bold"><b> </b></td></tr> <tr style="vertical-align: bottom; background-color: rgb(204,238,255)"> <td style="width: 28%; font-weight: bold; text-align: left">SCT Total Compensation</td><td style="width: 2%; font-weight: bold"> </td> <td style="width: 1%; font-weight: bold; text-align: left"> </td><td id="xdx_989_eecd--PeoTotalCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--DatukDrDorisWongSingEeMember_zHXBADAOuvea" style="width: 5%; font-weight: bold; text-align: right">470,785</td><td style="width: 1%; font-weight: bold; text-align: left"> </td><td style="width: 2%; font-weight: bold"> </td> <td style="width: 1%"> </td> <td id="xdx_98F_eecd--PeoTotalCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--MrDavidLazarMember_ze6uqIVrdC49" style="text-align: right; width: 5%"><b>66,250</b></td> <td style="width: 1%"><b> </b></td> <td style="width: 2%"><b> </b></td> <td style="width: 1%"><b> </b></td> <td id="xdx_98F_eecd--PeoTotalCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--MrSpiroRombotisMember_zkcMp8s34WX9" style="text-align: right; width: 5%"><b>847,436</b></td> <td style="width: 1%"> </td> <td style="width: 2%"> </td> <td style="width: 1%; font-weight: bold; text-align: left"> </td><td id="xdx_989_eecd--NonPeoNeoAvgTotalCompAmt_c20250101__20251231_zRtQrq6K1cf2" style="width: 5%; font-weight: bold; text-align: right">784,968</td><td style="width: 1%; font-weight: bold; text-align: left"> </td><td style="width: 2%; font-weight: bold"> </td> <td style="width: 1%; font-weight: bold; text-align: left"> </td><td id="xdx_986_eecd--PeoTotalCompAmt_c20240101__20241231_zQ2FYVW2QK63" style="width: 5%; font-weight: bold; text-align: right">585,000</td><td style="width: 1%; font-weight: bold; text-align: left"> </td><td style="width: 2%; font-weight: bold"> </td> <td style="width: 1%; font-weight: bold; text-align: left"> </td><td id="xdx_988_eecd--NonPeoNeoAvgTotalCompAmt_c20240101__20241231_z0hbnXETiw85" style="width: 5%; font-weight: bold; text-align: right">363,988</td><td style="width: 1%; font-weight: bold; text-align: left"> </td><td style="width: 2%; font-weight: bold"> </td> <td style="width: 1%; font-weight: bold; text-align: left"> </td><td id="xdx_981_eecd--PeoTotalCompAmt_c20230101__20231231_zkz5RYvY55Ha" style="width: 5%; font-weight: bold; text-align: right">661,049</td><td style="width: 1%; font-weight: bold; text-align: left"> </td><td style="width: 2%; font-weight: bold"> </td> <td style="width: 1%; font-weight: bold; text-align: left"> </td><td id="xdx_982_eecd--NonPeoNeoAvgTotalCompAmt_c20230101__20231231_zJgW61Gegrge" style="width: 5%; font-weight: bold; text-align: right">833,233</td><td style="width: 1%; font-weight: bold; text-align: left"> </td></tr> <tr style="vertical-align: bottom; background-color: White"> <td style="text-align: left">Subtract Reported SCT Stock Option Award Value ($)</td><td> </td> <td style="text-align: left"> </td><td id="xdx_985_eecd--AdjToCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--DatukDrDorisWongSingEeMember__ecd--AdjToCompAxis__custom--ReportedSCTStockOptionAwardValueMember_zy4vlDqBSI3e" style="text-align: right">(420,249</td><td style="text-align: left">)</td><td> </td> <td> </td> <td id="xdx_983_eecd--AdjToCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--MrDavidLazarMember__ecd--AdjToCompAxis__custom--ReportedSCTStockOptionAwardValueMember_zYpGBtLgvWpe" style="text-align: right">0</td> <td> </td> <td> </td> <td> </td> <td id="xdx_989_eecd--AdjToCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--MrSpiroRombotisMember__ecd--AdjToCompAxis__custom--ReportedSCTStockOptionAwardValueMember_zF9mq4rUoGKd" style="text-align: right">0</td> <td> </td> <td> </td> <td style="text-align: left"> </td><td id="xdx_989_eecd--AdjToCompAmt_c20250101__20251231__ecd--IndividualAxis__ecd--NonPeoNeoMember__ecd--AdjToCompAxis__custom--ReportedSCTStockOptionAwardValueMember_zfpaCwYOuyO8" style="text-align: right">(280,000</td><td style="text-align: left">)</td><td> </td> <td style="text-align: left"> </td><td id="xdx_986_eecd--AdjToCompAmt_c20240101__20241231__ecd--IndividualAxis__ecd--PeoMember__ecd--AdjToCompAxis__custom--ReportedSCTStockOptionAwardValueMember_zuiMsJ4ym5Ie" style="text-align: right">0</td><td style="text-align: left"> </td><td> </td> <td style="text-align: left"> </td><td id="xdx_982_eecd--AdjToCompAmt_c20240101__20241231__ecd--IndividualAxis__ecd--NonPeoNeoMember__ecd--AdjToCompAxis__custom--ReportedSCTStockOptionAwardValueMember_zX2AZuXYIuAk" style="text-align: right">0</td><td style="text-align: left"> </td><td> </td> <td style="text-align: left"> </td><td id="xdx_981_eecd--AdjToCompAmt_c20230101__20231231__ecd--IndividualAxis__ecd--PeoMember__ecd--AdjToCompAxis__custom--ReportedSCTStockOptionAwardValueMember_zf62HnkQ5OT4" style="text-align: right">(100,421</td><td style="text-align: left">)</td><td> </td> <td style="text-align: left"> </td><td id="xdx_98D_eecd--AdjToCompAmt_c20230101__20231231__ecd--IndividualAxis__ecd--NonPeoNeoMember__ecd--AdjToCompAxis__custom--ReportedSCTStockOptionAwardValueMember_zsFHDrT3qsBj" style="text-align: right">(118,167</td><td style="text-align: left">)</td></tr> <tr style="vertical-align: bottom; background-color: rgb(204,238,255)"> <td style="font-style: italic; text-align: left">Add Year-end Fair Value of Unvested Awards Granted in the Applicable Fiscal Year ($)</td><td> </td> <td style="text-align: left"> </td><td id="xdx_983_eecd--AdjToCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--DatukDrDorisWongSingEeMember__ecd--AdjToCompAxis__custom--YearEndFairValueOfUnvestedAwardsGrantedInTheApplicableFiscalYearMember_zjyPBZSMrbs5" style="text-align: right">0</td><td style="text-align: left"> </td><td> </td> <td> </td> <td id="xdx_988_eecd--AdjToCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--MrDavidLazarMember__ecd--AdjToCompAxis__custom--YearEndFairValueOfUnvestedAwardsGrantedInTheApplicableFiscalYearMember_zJuEZCMqlvw7" style="text-align: right">0</td> <td> </td> <td> </td> <td> </td> <td id="xdx_98A_eecd--AdjToCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--MrSpiroRombotisMember__ecd--AdjToCompAxis__custom--YearEndFairValueOfUnvestedAwardsGrantedInTheApplicableFiscalYearMember_z7rFvKQEIZq6" style="text-align: right">0</td> <td> </td> <td> </td> <td style="text-align: left"> </td><td id="xdx_989_eecd--AdjToCompAmt_c20250101__20251231__ecd--IndividualAxis__ecd--NonPeoNeoMember__ecd--AdjToCompAxis__custom--YearEndFairValueOfUnvestedAwardsGrantedInTheApplicableFiscalYearMember_zme4IykSNl77" style="text-align: right">0</td><td style="text-align: left"> </td><td> </td> <td style="text-align: left"> </td><td id="xdx_98C_eecd--AdjToCompAmt_c20240101__20241231__ecd--IndividualAxis__ecd--PeoMember__ecd--AdjToCompAxis__custom--YearEndFairValueOfUnvestedAwardsGrantedInTheApplicableFiscalYearMember_zP29NAa9EMjh" style="text-align: right">0</td><td style="text-align: left"> </td><td> </td> <td style="text-align: left"> </td><td id="xdx_986_eecd--AdjToCompAmt_c20240101__20241231__ecd--IndividualAxis__ecd--NonPeoNeoMember__ecd--AdjToCompAxis__custom--YearEndFairValueOfUnvestedAwardsGrantedInTheApplicableFiscalYearMember_zKlttFXXoGS8" style="text-align: right">0</td><td style="text-align: left"> </td><td> </td> <td style="text-align: left"> </td><td id="xdx_988_eecd--AdjToCompAmt_c20230101__20231231__ecd--IndividualAxis__ecd--PeoMember__ecd--AdjToCompAxis__custom--YearEndFairValueOfUnvestedAwardsGrantedInTheApplicableFiscalYearMember_zhkQe4BGtHR8" style="text-align: right">21,961</td><td style="text-align: left"> </td><td> </td> <td style="text-align: left"> </td><td id="xdx_983_eecd--AdjToCompAmt_c20230101__20231231__ecd--IndividualAxis__ecd--NonPeoNeoMember__ecd--AdjToCompAxis__custom--YearEndFairValueOfUnvestedAwardsGrantedInTheApplicableFiscalYearMember_zLZaf9krZg9b" style="text-align: right">26,051</td><td style="text-align: left"> </td></tr> <tr style="vertical-align: bottom; background-color: White"> <td style="font-style: italic; text-align: left">Add Change in Fair Value of Awards Granted in Prior Years Outstanding and Unvested as of the Applicable Fiscal Year End ($)</td><td> </td> <td style="text-align: left"> </td><td id="xdx_98B_eecd--AdjToCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--DatukDrDorisWongSingEeMember__ecd--AdjToCompAxis__custom--ChangeInFairValueOfAwardsGrantedInPriorYearsOutstandingAndUnvestedAsOfTheApplicableFiscalYearEndMember_z9J3IYeslW12" style="text-align: right">0</td><td style="text-align: left"> </td><td> </td> <td> </td> <td style="text-align: right"><p id="xdx_98C_eecd--AdjToCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--MrDavidLazarMember__ecd--AdjToCompAxis__custom--ChangeInFairValueOfAwardsGrantedInPriorYearsOutstandingAndUnvestedAsOfTheApplicableFiscalYearEndMember_zkmkoBy76gS6" style="margin: 0; text-align: right">0</p></td> <td> </td> <td> </td> <td> </td> <td id="xdx_989_eecd--AdjToCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--MrSpiroRombotisMember__ecd--AdjToCompAxis__custom--ChangeInFairValueOfAwardsGrantedInPriorYearsOutstandingAndUnvestedAsOfTheApplicableFiscalYearEndMember_zKFZpDUXjJHj" style="text-align: right">0</td> <td> </td> <td> </td> <td style="text-align: left"> </td><td id="xdx_98E_eecd--AdjToCompAmt_c20250101__20251231__ecd--IndividualAxis__ecd--NonPeoNeoMember__ecd--AdjToCompAxis__custom--ChangeInFairValueOfAwardsGrantedInPriorYearsOutstandingAndUnvestedAsOfTheApplicableFiscalYearEndMember_zaQCjVzeqbQ6" style="text-align: right">0</td><td style="text-align: left"> </td><td> </td> <td style="text-align: left"> </td><td id="xdx_98C_eecd--AdjToCompAmt_c20240101__20241231__ecd--IndividualAxis__ecd--PeoMember__ecd--AdjToCompAxis__custom--ChangeInFairValueOfAwardsGrantedInPriorYearsOutstandingAndUnvestedAsOfTheApplicableFiscalYearEndMember_zc78p58o6V2c" style="text-align: right">(21,986</td><td style="text-align: left">)</td><td> </td> <td style="text-align: left"> </td><td id="xdx_988_eecd--AdjToCompAmt_c20240101__20241231__ecd--IndividualAxis__ecd--NonPeoNeoMember__ecd--AdjToCompAxis__custom--ChangeInFairValueOfAwardsGrantedInPriorYearsOutstandingAndUnvestedAsOfTheApplicableFiscalYearEndMember_zGs4e5TPJCs4" style="text-align: right">(13,042</td><td style="text-align: left">)</td><td> </td> <td style="text-align: left"> </td><td id="xdx_98D_eecd--AdjToCompAmt_c20230101__20231231__ecd--IndividualAxis__ecd--PeoMember__ecd--AdjToCompAxis__custom--ChangeInFairValueOfAwardsGrantedInPriorYearsOutstandingAndUnvestedAsOfTheApplicableFiscalYearEndMember_zPHU1xrzrq11" style="text-align: right">(164,307</td><td style="text-align: left">)</td><td> </td> <td style="text-align: left"> </td><td id="xdx_986_eecd--AdjToCompAmt_c20230101__20231231__ecd--IndividualAxis__ecd--NonPeoNeoMember__ecd--AdjToCompAxis__custom--ChangeInFairValueOfAwardsGrantedInPriorYearsOutstandingAndUnvestedAsOfTheApplicableFiscalYearEndMember_zsmM7i126Xr9" style="text-align: right">(172,971</td><td style="text-align: left">)</td></tr> <tr style="vertical-align: bottom; background-color: rgb(204,238,255)"> <td style="font-style: italic; text-align: left; padding-bottom: 1pt">Add Change in Fair Value of Awards Granted in Prior Years that Vested during the Applicable Year as of the Vesting Date</td><td style="padding-bottom: 1pt"> </td> <td style="border-bottom: Black 1pt solid; text-align: right"> </td><td id="xdx_982_eecd--AdjToCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--DatukDrDorisWongSingEeMember__ecd--AdjToCompAxis__custom--ChangeInFairValueOfAwardsGrantedInPriorYearsThatVestedDuringTheApplicableYearAsOfTheVestingDateMember_zkjJbsq1gTZf" style="border-bottom: Black 1pt solid; text-align: right">0</td><td style="padding-bottom: 1pt; text-align: left"> </td><td style="padding-bottom: 1pt"> </td> <td style="border-bottom: Black 1pt solid; text-align: right"> </td> <td style="border-bottom: Black 1pt solid; text-align: right"><p id="xdx_98A_eecd--AdjToCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--MrDavidLazarMember__ecd--AdjToCompAxis__custom--ChangeInFairValueOfAwardsGrantedInPriorYearsThatVestedDuringTheApplicableYearAsOfTheVestingDateMember_zOlf7kB33h0f" style="margin: 0; text-align: right">0</p></td> <td style="padding-bottom: 1pt"> </td> <td style="padding-bottom: 1pt"> </td> <td style="border-bottom: Black 1pt solid; text-align: right"> </td> <td id="xdx_987_eecd--AdjToCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--MrSpiroRombotisMember__ecd--AdjToCompAxis__custom--ChangeInFairValueOfAwardsGrantedInPriorYearsThatVestedDuringTheApplicableYearAsOfTheVestingDateMember_zePiPOkXpxy3" style="border-bottom: Black 1pt solid; text-align: right">0</td> <td style="padding-bottom: 1pt"> </td> <td style="padding-bottom: 1pt"> </td> <td style="border-bottom: Black 1pt solid; text-align: right"> </td><td id="xdx_982_eecd--AdjToCompAmt_c20250101__20251231__ecd--IndividualAxis__ecd--NonPeoNeoMember__ecd--AdjToCompAxis__custom--ChangeInFairValueOfAwardsGrantedInPriorYearsThatVestedDuringTheApplicableYearAsOfTheVestingDateMember_zccWAuVHVqs5" style="border-bottom: Black 1pt solid; text-align: right">0</td><td style="padding-bottom: 1pt; text-align: left"> </td><td style="padding-bottom: 1pt"> </td> <td style="border-bottom: Black 1pt solid; text-align: right"> </td><td id="xdx_98A_eecd--AdjToCompAmt_c20240101__20241231__ecd--IndividualAxis__ecd--PeoMember__ecd--AdjToCompAxis__custom--ChangeInFairValueOfAwardsGrantedInPriorYearsThatVestedDuringTheApplicableYearAsOfTheVestingDateMember_zkKuuBofEaNh" style="border-bottom: Black 1pt solid; text-align: right">(15,308</td><td style="padding-bottom: 1pt; text-align: left">)</td><td style="padding-bottom: 1pt"> </td> <td style="border-bottom: Black 1pt solid; text-align: right"> </td><td id="xdx_988_eecd--AdjToCompAmt_c20240101__20241231__ecd--IndividualAxis__ecd--NonPeoNeoMember__ecd--AdjToCompAxis__custom--ChangeInFairValueOfAwardsGrantedInPriorYearsThatVestedDuringTheApplicableYearAsOfTheVestingDateMember_zjiS0dkmbAef" style="border-bottom: Black 1pt solid; text-align: right">(8,057</td><td style="padding-bottom: 1pt; text-align: left">)</td><td style="padding-bottom: 1pt"> </td> <td style="border-bottom: Black 1pt solid; text-align: right"> </td><td id="xdx_980_eecd--AdjToCompAmt_c20230101__20231231__ecd--IndividualAxis__ecd--PeoMember__ecd--AdjToCompAxis__custom--ChangeInFairValueOfAwardsGrantedInPriorYearsThatVestedDuringTheApplicableYearAsOfTheVestingDateMember_z0uFfbFCRJfk" style="border-bottom: Black 1pt solid; text-align: right">(352,475</td><td style="padding-bottom: 1pt; text-align: left">)</td><td style="padding-bottom: 1pt"> </td> <td style="border-bottom: Black 1pt solid; text-align: right"> </td><td id="xdx_987_eecd--AdjToCompAmt_c20230101__20231231__ecd--IndividualAxis__ecd--NonPeoNeoMember__ecd--AdjToCompAxis__custom--ChangeInFairValueOfAwardsGrantedInPriorYearsThatVestedDuringTheApplicableYearAsOfTheVestingDateMember_zQzuRmWyB0m2" style="border-bottom: Black 1pt solid; text-align: right">(395,470</td><td style="padding-bottom: 1pt; text-align: left">)</td></tr> <tr style="vertical-align: bottom; background-color: White"> <td style="font-weight: bold; text-align: left; padding-bottom: 2.5pt">Total Compensation Actually Paid</td><td style="font-weight: bold; padding-bottom: 2.5pt"> </td> <td style="border-bottom: Black 2.5pt double; font-weight: bold; text-align: right"> </td><td id="xdx_98B_eecd--PeoActuallyPaidCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--DatukDrDorisWongSingEeMember_z0SEJ7QMrqpe" style="border-bottom: Black 2.5pt double; font-weight: bold; text-align: right">50,536</td><td style="padding-bottom: 2.5pt; font-weight: bold; text-align: left"> </td><td style="font-weight: bold; padding-bottom: 2.5pt"> </td> <td style="border-bottom: Black 2.5pt double; font-weight: bold; text-align: right"> </td> <td id="xdx_987_eecd--PeoActuallyPaidCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--MrDavidLazarMember_zIm1vEZ8jsKl" style="border-bottom: Black 2.5pt double; text-align: right"><b>66,250</b></td> <td style="padding-bottom: 2.5pt"><b> </b></td> <td style="padding-bottom: 2.5pt"><b> </b></td> <td style="border-bottom: Black 2.5pt double; font-weight: bold; text-align: right"><b> </b></td> <td id="xdx_98E_eecd--PeoActuallyPaidCompAmt_c20250101__20251231__ecd--IndividualAxis__custom--MrSpiroRombotisMember_zpkQqcfIf9Jg" style="border-bottom: Black 2.5pt double; text-align: right"><b>847,436</b></td> <td style="padding-bottom: 2.5pt"><b> </b></td> <td style="padding-bottom: 2.5pt"> </td> <td style="border-bottom: Black 2.5pt double; font-weight: bold; text-align: right"> </td><td id="xdx_985_eecd--NonPeoNeoAvgCompActuallyPaidAmt_c20250101__20251231_zIxFpX9IFz9g" style="border-bottom: Black 2.5pt double; font-weight: bold; text-align: right">504,968</td><td style="padding-bottom: 2.5pt; font-weight: bold; text-align: left"> </td><td style="font-weight: bold; padding-bottom: 2.5pt"> </td> <td style="border-bottom: Black 2.5pt double; font-weight: bold; text-align: right"> </td><td id="xdx_989_eecd--PeoActuallyPaidCompAmt_c20240101__20241231_zjQHqsdM56J5" style="border-bottom: Black 2.5pt double; font-weight: bold; text-align: right">547,706</td><td style="padding-bottom: 2.5pt; font-weight: bold; text-align: left"> </td><td style="font-weight: bold; padding-bottom: 2.5pt"> </td> <td style="border-bottom: Black 2.5pt double; font-weight: bold; text-align: right"> </td><td id="xdx_982_eecd--NonPeoNeoAvgCompActuallyPaidAmt_c20240101__20241231_zHHikrjXVozi" style="border-bottom: Black 2.5pt double; font-weight: bold; text-align: right">342,889</td><td style="padding-bottom: 2.5pt; font-weight: bold; text-align: left"> </td><td style="font-weight: bold; padding-bottom: 2.5pt"> </td> <td style="border-bottom: Black 2.5pt double; font-weight: bold; text-align: right"> </td><td id="xdx_98C_eecd--PeoActuallyPaidCompAmt_c20230101__20231231_zO7Q5E8Epdzh" style="border-bottom: Black 2.5pt double; font-weight: bold; text-align: right">65,807</td><td style="padding-bottom: 2.5pt; font-weight: bold; text-align: left"> </td><td style="font-weight: bold; padding-bottom: 2.5pt"> </td> <td style="border-bottom: Black 2.5pt double; font-weight: bold; text-align: right"> </td><td id="xdx_98E_eecd--NonPeoNeoAvgCompActuallyPaidAmt_c20230101__20231231_zFXjKTy677Yf" style="border-bottom: Black 2.5pt double; font-weight: bold; text-align: right">172,676</td><td style="padding-bottom: 2.5pt; font-weight: bold; text-align: left"> </td></tr> </table> <p style="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0pt; margin-bottom: 0pt"> </p> 470785 66250 847436 784968 585000 363988 661049 833233 -420249 0 0 -280000 0 0 -100421 -118167 0 0 0 0 0 0 21961 26051 0 0 0 0 -21986 -13042 -164307 -172971 0 0 0 0 -15308 -8057 -352475 -395470 50536 66250 847436 504968 547706 342889 65807 172676 <p id="xdx_893_eecd--CompActuallyPaidVsTotalShareholderRtnTextBlock_dU_ztV2S2ona1o3" style="font: 10pt Times New Roman, Times, Serif; display: none; margin: 0pt; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"> </span></p> <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Relationship Between CEO and Non-CEO NEO Compensation Actually Paid and Company Total Shareholder Return (“TSR”)</b></span></p> <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"> </span></p> <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; text-indent: 0.25in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The following chart sets forth the relationship between Compensation Actually Paid to our CEO, the average of Compensation Actually Paid to our Non-CEO NEOs, and the Company’s cumulative TSR over the three most recently completed fiscal years.</span></p> <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"> </span></p> <p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><img alt="" src="formdef14a_002.jpg"/></span></p> <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"></p> <p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p> <p id="xdx_89C_eecd--CompActuallyPaidVsNetIncomeTextBlock_dU_z7NiLB6grYxc" style="font: 10pt Times New Roman, Times, Serif; display: none; margin: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"> </span></p> <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Relationship Between CEO and Non-CEO NEO Compensation Actually Paid and Net Income (Loss) </i></b></span></p> <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"> </span></p> <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The following chart sets forth the relationship between Compensation Actually Paid to our CEO, the average of Compensation Actually Paid to our Non-CEO NEOs, and our Net Income (Loss) during the three most recently completed fiscal years.</span></p> <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"> </span></p> <p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><img alt="" src="formdef14a_003.jpg"/><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p> Amounts in this column represent the “Total” column set forth in the Summary Compensation Table (“SCT”) in the “Executive and Director Compensation” section. See the footnotes to the SCT for further details regarding the amounts in these columns. The dollar amounts reported in these columns represent the amounts of “compensation actually paid.” The Amounts are computed in accordance with SEC rules by deducting and adding the following amounts from the “Total” column of the SCT (pursuant to SEC rules, fair value at each measurement date is computed in a manner consistent with the fair value methodology used to account for share-based payments in our financial statements under GAAP): Cumulative Total Shareholder Return (“TSR”) measures the cumulative value of $100 invested on the last trading day before the earliest fiscal year in the table, or December 31, 2021, including the reinvestment of dividends, through and including the end of the applicable fiscal year for which TSR is calculated, or December 31, 2023, December 31, 2024 and December 31, 2025. We did not pay dividends in the periods presented. The dollar amounts reported represent the amount of net loss reflected in the Company’s audited financial statements for the applicable year.