Stockholders' Equity - Schedule of Reserved Shares of Common Stock for Future Issuance (Detail) - shares	Mar. 31, 2026	Dec. 31, 2025
Class of Stock [Line Items]
Common shares reserved for future issuance	85,454,478	34,355,601
2024 Plan
Class of Stock [Line Items]
Common shares reserved for future issuance	2,308,196	4,469,906
2014 Employee Stock Purchase Plan
Class of Stock [Line Items]
Common shares reserved for future issuance	1,339,099	1,367,900
2015 Plan
Class of Stock [Line Items]
Common shares reserved for future issuance	666,550	665,634
Warrant \| December 2020 Public Offering
Class of Stock [Line Items]
Common shares reserved for future issuance	3,200,000	3,200,000
Warrant \| Warrants to Purchase Common Stock Associated With April 2022 Public Offering
Class of Stock [Line Items]
Common shares reserved for future issuance	15,000,000	15,000,000
Warrant \| Warrants Associated With March 2026 Private Placement
Class of Stock [Line Items]
Common shares reserved for future issuance	43,500,000	0
Warrant \| March 2026 Private Placement
Class of Stock [Line Items]
Common shares reserved for future issuance	8,750,000	0
Warrant \| April 2022 Public Offering
Class of Stock [Line Items]
Common shares reserved for future issuance	3,189,815	3,189,815
Warrant \| Warrants to purchase common stock associated with Loan Agreement
Class of Stock [Line Items]
Common shares reserved for future issuance	198,811	198,811
Warrant \| Warrants to purchase common stock associated with Danforth
Class of Stock [Line Items]
Common shares reserved for future issuance	50,000	50,000
Restricted Stock Units
Class of Stock [Line Items]
Common shares reserved for future issuance	3,732,599	2,663,923
Stock options
Class of Stock [Line Items]
Common shares reserved for future issuance	3,519,408	3,549,612