v3.26.1
Pay vs Performance Disclosure - USD ($)
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Pay vs Performance Disclosure      
Pay vs Performance Disclosure, Table
Pay versus Performance
 
Year
 
Summary
 Compensation 
Table Total
for PEO(1)
($)
 
 Compensation 
Actually Paid
to PEO(2)
($)
 
Summary
Compensation
Table Total
for former
PEO(1) ($)
   
Compensation
Actually Paid
to former
PEO(2) ($)
   
Average
Summary
Compensation
Table Total
for
Non-PEO

Named
Executive
Officers(3)
($)
   
Average
Compensation
Actually Paid
to
Non-PEO

Named
Executive
Officers(4)
($)
   
Value of Initial Fixed $100
Investment Based On:
   
Net
Income(6)
(
in thousands
)
($)
 
 
Total Shareholder
Return(5)
($)
 
(a)   (b)   (c)   (b)     (c)     (d)     (e)     (f)     (h)  
2025
  2,248,568   1,646,376                     913,398       574,491       9.71       (136,315
2024
            4,175,069       1,594,718       3,502,850       1,265,833       16.35       (186,262
2023
            3,522,750       (360,474     2,878,537       617,776       37.07       (160,928
 
  (1)
For 2025, the dollar amounts reported in column (b) are the amounts of total compensation reported for Bahram Valamehr, corresponding to the applicable year in the “Total” column of the applicable Summary Compensation Table. For the years 2023 and 2024, the dollar amounts reported in column (b) are the amounts of total compensation report for our former PEO, J. Scott Wolchko, corresponding to the applicable year in the “Total” column of the applicable Summary Compensation Table.
  (2)
The dollar amounts reported in column (c) represent the amount of “compensation actually paid” to Dr. Valamehr or Mr. Wolchko, as applicable, as computed in accordance with Item 402(v) of Regulation
S-K
during the applicable year. The dollar amounts do not reflect the actual amount of compensation earned by or paid to Dr. Valamehr or Mr. Wolchko during the applicable year. In accordance with the requirements of Item 402(v) of Regulation
S-K,
the following adjustments were made to Dr. Valamehr’s total compensation for the applicable year to determine the compensation actually paid:
 
Year
 
Reported Summary
Compensation Table
Total for PEO
($)
   
Reported Value of
Equity Awards(a)
($)
   
Equity Award
Adjustments(b)
($)
   
Compensation
Actually
Paid to PEO
($)
 
2025
    2,248,568       (1,283,868     681,676       1,646,376  
 
  (a)
The grant date fair value of equity awards represents the total of the amounts reported in the “Option Awards” and “Stock Awards” columns in the Summary Compensation Table for the applicable year.
  (b)
The valuation assumptions used to calculate fair values did not materially differ from those disclosed at the time of grant. The amounts deducted or added in calculating the equity award adjustments are as follows:
 
Year
 
Year End Fair
Value of
Outstanding
and Unvested
Equity
Awards
Granted in the
Year
($)
   
Year over Year
Change in Fair
Value of
Outstanding
and Unvested
Equity Awards
Granted in
Prior Years
($)
   
Fair Value
as of
Vesting
Date of
Equity
Awards
Granted
and
Vested in
the Year
($)
   
Year over
Year Change
in Fair Value
of Equity
Awards
Granted in
Prior Years
that Vested in
the Year
($)
   
Fair Value at
the End of the
Prior Year of
Equity
Awards that
Failed to Meet
Vesting
Conditions in
the Year
($)
   
Value of
Dividends or
Other Earnings
Paid on Stock or
Option Awards
not Otherwise
Reflected in Fair
Value or Total
Compensation
($)
   
Total Equity
Award
Adjustments
 
2025
    748,914       (262,055     361,343       (166,526     —        —        681,676  
 
In accordance with the requirements of Item 402(v) of Regulation
S-K,
the following adjustments were made to Mr. Wolchko’s total compensation for the applicable years to determine the compensation actually paid:
 
Year
 
Reported Summary
Compensation Table
Total for former
PEO
($)
   
Reported Value of
Equity Awards(a)
($)
   
Equity Award
Adjustments(b)
($)
   
Compensation
Actually
Paid to
former PEO
($)
 
2024
    4,175,069       (3,090,469     510,118       1,594,718  
2023
    3,522,750       (2,602,350     (1,280,874     (360,474
 
  (a)
The grant date fair value of equity awards represents the total of the amounts reported in the “Option Awards” and “Stock Awards” columns in the Summary Compensation Table for the applicable year.
  (b)
The valuation assumptions used to calculate fair values did not materially differ from those disclosed at the time of grant. The amounts deducted or added in calculating the equity award adjustments are as follows:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Year
 
Year End Fair
Value of
Outstanding
and Unvested
Equity
Awards
Granted in the
Year
($)
   
Year over Year
Change in Fair
Value of
Outstanding
and Unvested
Equity Awards
Granted in
Prior Years
($)
   
Fair Value
as of
Vesting
Date of
Equity
Awards
Granted
and
Vested in
the Year
($)
   
Year over
Year Change
in Fair Value
of Equity
Awards
Granted in
Prior Years
that Vested in
the Year
($)
   
Fair Value at
the End of the
Prior Year of
Equity
Awards that
Failed to Meet
Vesting
Conditions in
the Year
($)
   
Value of
Dividends or
Other Earnings
Paid on Stock or
Option Awards
not Otherwise
Reflected in Fair
Value or Total
Compensation
($)
   
Total Equity
Award
Adjustments
 
2024
    392,188       (368,844     450,541       36,233       —        —        510,118  
2023
    1,048,478       (1,798,128     489,062       (1,020,286     —        —        (1,280,874
 
  (3)
The dollar amounts reported in column (d) represent the average of the amounts reported for our company’s named executive officers as a group (excluding the applicable year’s PEO) in the “Total” column of the Summary Compensation Table in each applicable year. The names of each of the named executive officers (excluding the applicable year’s PEO) included for purposes of calculating the average amounts in each applicable year are as follows:
 
Year
  
Non-PEO
NEOs
2025    Kamal Adawi, Cindy Tahl
2024    Bahram Valamehr, Cindy Tahl
2023    Edward Dulac, Bahram Valamehr, Cindy Tahl
 
  (4)
The dollar amounts reported in column (e) represent the average amount of “compensation actually paid” to the named executive officers as a group (excluding the applicable year’s PEO), as computed in accordance with Item 402(v) of Regulation
S-K.
The dollar amounts do not reflect the actual average amount of compensation earned by or paid to the named executive officers as a group (excluding the applicable year’s PEO) during the applicable year. In accordance with the requirements of Item 402(v) of Regulation
S-K,
the following adjustments were made to average total compensation for the named
 
  executive officers as a group (excluding the applicable year’s PEO) for each year to determine the compensation actually paid:
 
Year
 
Reported Summary
Compensation
Table Total for
Non-PEO
NEOs
($)
   
Reported Value of
Equity Awards(a)
($)
   
Equity Award
Adjustments(b)
($)
   
Compensation Actually
Paid to Non-
PEO NEOs
($)
 
2025
    913,398       (475,398     136,491       574,491  
2024
    3,502,850       (2,842,250     605,233       1,265,833  
2023
    2,878,537       (2,255,370     (5,391     617,776  
 
  (a)
The grant date fair value of equity awards represents the total of the amounts reported in the “Option Awards” and “Stock Awards” columns in the Summary Compensation Table for the applicable year.
  (b)
The valuation assumptions used to calculate fair values did not materially differ from those disclosed at the time of grant. The amounts deducted or added in calculating the equity award adjustments are as follows:
 
Year
 
Year End Fair
Value of
Outstanding
and Unvested
Equity
Awards
Granted in the
Year
($)
   
Year over Year
Change in Fair
Value of
Outstanding
and Unvested
Equity Awards
Granted in
Prior Years
($)
   
Fair Value
as of
Vesting
Date of
Equity
Awards
Granted
and Vested
in the Year
($)
   
Year over
Year Change
in Fair Value
of Equity
Awards
Granted in
Prior Years
that Vested in
the Year
($)
   
Fair Value at
the End of the
Prior Year of
Equity
Awards that
Failed to
Meet Vesting
Conditions in
the Year
($)
   
Value of
Dividends or
Other Earnings
Paid on Stock or
Option Awards
not Otherwise
Reflected in Fair
Value or Total
Compensation
($)
   
Total Equity
Award
Adjustments
 
2025
    305,902       (128,306     38,036       (79,141     —        —        136,491  
2024
    687,463       (498,975     394,226       22,519       —        —        605,233  
2023
    908,685       (1,043,584     423,854       (294,346     —        —        (5,391
 
  (5)
The calculation of Cumulative TSR assumes that $100 was invested in our common stock as of the market close on December 31, 2022.
  (6)
The dollar amounts reported represent the amount of net income (loss) reflected in our consolidated audited financial statements for the applicable year.
   
Named Executive Officers, Footnote
  (3)
The dollar amounts reported in column (d) represent the average of the amounts reported for our company’s named executive officers as a group (excluding the applicable year’s PEO) in the “Total” column of the Summary Compensation Table in each applicable year. The names of each of the named executive officers (excluding the applicable year’s PEO) included for purposes of calculating the average amounts in each applicable year are as follows:
 
Year
  
Non-PEO
NEOs
2025    Kamal Adawi, Cindy Tahl
2024    Bahram Valamehr, Cindy Tahl
2023    Edward Dulac, Bahram Valamehr, Cindy Tahl
   
Adjustment To PEO Compensation, Footnote
  (2)
The dollar amounts reported in column (c) represent the amount of “compensation actually paid” to Dr. Valamehr or Mr. Wolchko, as applicable, as computed in accordance with Item 402(v) of Regulation
S-K
during the applicable year. The dollar amounts do not reflect the actual amount of compensation earned by or paid to Dr. Valamehr or Mr. Wolchko during the applicable year. In accordance with the requirements of Item 402(v) of Regulation
S-K,
the following adjustments were made to Dr. Valamehr’s total compensation for the applicable year to determine the compensation actually paid:
 
Year
 
Reported Summary
Compensation Table
Total for PEO
($)
   
Reported Value of
Equity Awards(a)
($)
   
Equity Award
Adjustments(b)
($)
   
Compensation
Actually
Paid to PEO
($)
 
2025
    2,248,568       (1,283,868     681,676       1,646,376  
 
  (a)
The grant date fair value of equity awards represents the total of the amounts reported in the “Option Awards” and “Stock Awards” columns in the Summary Compensation Table for the applicable year.
  (b)
The valuation assumptions used to calculate fair values did not materially differ from those disclosed at the time of grant. The amounts deducted or added in calculating the equity award adjustments are as follows:
 
Year
 
Year End Fair
Value of
Outstanding
and Unvested
Equity
Awards
Granted in the
Year
($)
   
Year over Year
Change in Fair
Value of
Outstanding
and Unvested
Equity Awards
Granted in
Prior Years
($)
   
Fair Value
as of
Vesting
Date of
Equity
Awards
Granted
and
Vested in
the Year
($)
   
Year over
Year Change
in Fair Value
of Equity
Awards
Granted in
Prior Years
that Vested in
the Year
($)
   
Fair Value at
the End of the
Prior Year of
Equity
Awards that
Failed to Meet
Vesting
Conditions in
the Year
($)
   
Value of
Dividends or
Other Earnings
Paid on Stock or
Option Awards
not Otherwise
Reflected in Fair
Value or Total
Compensation
($)
   
Total Equity
Award
Adjustments
 
2025
    748,914       (262,055     361,343       (166,526     —        —        681,676  
 
In accordance with the requirements of Item 402(v) of Regulation
S-K,
the following adjustments were made to Mr. Wolchko’s total compensation for the applicable years to determine the compensation actually paid:
 
Year
 
Reported Summary
Compensation Table
Total for former
PEO
($)
   
Reported Value of
Equity Awards(a)
($)
   
Equity Award
Adjustments(b)
($)
   
Compensation
Actually
Paid to
former PEO
($)
 
2024
    4,175,069       (3,090,469     510,118       1,594,718  
2023
    3,522,750       (2,602,350     (1,280,874     (360,474
 
  (a)
The grant date fair value of equity awards represents the total of the amounts reported in the “Option Awards” and “Stock Awards” columns in the Summary Compensation Table for the applicable year.
  (b)
The valuation assumptions used to calculate fair values did not materially differ from those disclosed at the time of grant. The amounts deducted or added in calculating the equity award adjustments are as follows:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Year
 
Year End Fair
Value of
Outstanding
and Unvested
Equity
Awards
Granted in the
Year
($)
   
Year over Year
Change in Fair
Value of
Outstanding
and Unvested
Equity Awards
Granted in
Prior Years
($)
   
Fair Value
as of
Vesting
Date of
Equity
Awards
Granted
and
Vested in
the Year
($)
   
Year over
Year Change
in Fair Value
of Equity
Awards
Granted in
Prior Years
that Vested in
the Year
($)
   
Fair Value at
the End of the
Prior Year of
Equity
Awards that
Failed to Meet
Vesting
Conditions in
the Year
($)
   
Value of
Dividends or
Other Earnings
Paid on Stock or
Option Awards
not Otherwise
Reflected in Fair
Value or Total
Compensation
($)
   
Total Equity
Award
Adjustments
 
2024
    392,188       (368,844     450,541       36,233       —        —        510,118  
2023
    1,048,478       (1,798,128     489,062       (1,020,286     —        —        (1,280,874
   
Non-PEO NEO Average Total Compensation Amount $ 913,398 $ 3,502,850 $ 2,878,537
Non-PEO NEO Average Compensation Actually Paid Amount $ 574,491 1,265,833 617,776
Adjustment to Non-PEO NEO Compensation Footnote
  (4)
The dollar amounts reported in column (e) represent the average amount of “compensation actually paid” to the named executive officers as a group (excluding the applicable year’s PEO), as computed in accordance with Item 402(v) of Regulation
S-K.
The dollar amounts do not reflect the actual average amount of compensation earned by or paid to the named executive officers as a group (excluding the applicable year’s PEO) during the applicable year. In accordance with the requirements of Item 402(v) of Regulation
S-K,
the following adjustments were made to average total compensation for the named
 
  executive officers as a group (excluding the applicable year’s PEO) for each year to determine the compensation actually paid:
 
Year
 
Reported Summary
Compensation
Table Total for
Non-PEO
NEOs
($)
   
Reported Value of
Equity Awards(a)
($)
   
Equity Award
Adjustments(b)
($)
   
Compensation Actually
Paid to Non-
PEO NEOs
($)
 
2025
    913,398       (475,398     136,491       574,491  
2024
    3,502,850       (2,842,250     605,233       1,265,833  
2023
    2,878,537       (2,255,370     (5,391     617,776  
 
  (a)
The grant date fair value of equity awards represents the total of the amounts reported in the “Option Awards” and “Stock Awards” columns in the Summary Compensation Table for the applicable year.
  (b)
The valuation assumptions used to calculate fair values did not materially differ from those disclosed at the time of grant. The amounts deducted or added in calculating the equity award adjustments are as follows:
 
Year
 
Year End Fair
Value of
Outstanding
and Unvested
Equity
Awards
Granted in the
Year
($)
   
Year over Year
Change in Fair
Value of
Outstanding
and Unvested
Equity Awards
Granted in
Prior Years
($)
   
Fair Value
as of
Vesting
Date of
Equity
Awards
Granted
and Vested
in the Year
($)
   
Year over
Year Change
in Fair Value
of Equity
Awards
Granted in
Prior Years
that Vested in
the Year
($)
   
Fair Value at
the End of the
Prior Year of
Equity
Awards that
Failed to
Meet Vesting
Conditions in
the Year
($)
   
Value of
Dividends or
Other Earnings
Paid on Stock or
Option Awards
not Otherwise
Reflected in Fair
Value or Total
Compensation
($)
   
Total Equity
Award
Adjustments
 
2025
    305,902       (128,306     38,036       (79,141     —        —        136,491  
2024
    687,463       (498,975     394,226       22,519       —        —        605,233  
2023
    908,685       (1,043,584     423,854       (294,346     —        —        (5,391
   
Compensation Actually Paid vs. Total Shareholder Return
Description of Relationship Between PEO and
Non-PEO
NEO Compensation Actually Paid and Company Total Shareholder Return (“TSR”)
The following chart sets forth the relationship between Compensation Actually Paid to our PEOs, the average of Compensation Actually Paid to our
Non-PEO
NEOs, and the Company’s cumulative TSR over the three most recently completed fiscal years.
 
LOGO
 
   
Compensation Actually Paid vs. Net Income
Description of Relationship Between PEO and
Non-PEO
NEO Compensation Actually Paid and Net Income
The following chart sets forth the relationship between Compensation Actually Paid to our PEOs, the average of Compensation Actually Paid to our
Non-PEO
NEOs, and our Net Income during the three most recently completed fiscal years.
 
LOGO
   
Total Shareholder Return Amount $ 9.71 16.35 37.07
Net Income (Loss) (136,315,000) (186,262,000) (160,928,000)
Bahram Valamehr [Member]      
Pay vs Performance Disclosure      
PEO Total Compensation Amount 2,248,568    
PEO Actually Paid Compensation Amount $ 1,646,376    
PEO Name Bahram Valamehr    
J. Scott Wolchko [Member]      
Pay vs Performance Disclosure      
PEO Total Compensation Amount   4,175,069 3,522,750
PEO Actually Paid Compensation Amount   $ 1,594,718 $ (360,474)
PEO Name   J. Scott Wolchko J. Scott Wolchko
PEO | Bahram Valamehr [Member] | Equity Awards Adjustments      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount $ 681,676    
PEO | Bahram Valamehr [Member] | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 748,914    
PEO | Bahram Valamehr [Member] | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (262,055)    
PEO | Bahram Valamehr [Member] | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 361,343    
PEO | Bahram Valamehr [Member] | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (166,526)    
PEO | Bahram Valamehr [Member] | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 0    
PEO | Bahram Valamehr [Member] | Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 0    
PEO | Bahram Valamehr [Member] | Reported Value Of Equity Awards [Member]      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (1,283,868)    
PEO | J. Scott Wolchko [Member] | Equity Awards Adjustments      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount   $ 510,118 $ (1,280,874)
PEO | J. Scott Wolchko [Member] | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount   392,188 1,048,478
PEO | J. Scott Wolchko [Member] | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount   (368,844) (1,798,128)
PEO | J. Scott Wolchko [Member] | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount   450,541 489,062
PEO | J. Scott Wolchko [Member] | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount   36,233 (1,020,286)
PEO | J. Scott Wolchko [Member] | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount   0 0
PEO | J. Scott Wolchko [Member] | Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount   0 0
PEO | J. Scott Wolchko [Member] | Reported Value Of Equity Awards [Member]      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount   (3,090,469) (2,602,350)
Non-PEO NEO | Equity Awards Adjustments      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 136,491 605,233 (5,391)
Non-PEO NEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 305,902 687,463 908,685
Non-PEO NEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (128,306) (498,975) (1,043,584)
Non-PEO NEO | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 38,036 394,226 423,854
Non-PEO NEO | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (79,141) 22,519 (294,346)
Non-PEO NEO | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 0 0 0
Non-PEO NEO | Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 0 0 0
Non-PEO NEO | Reported Value Of Equity Awards [Member]      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount $ (475,398) $ (2,842,250) $ (2,255,370)