144: Issuer Information

Name of Issuer

ILLUMINA, INC.

SEC File Number

001-35406

Address of Issuer

5200 ILLUMINA WAY
SAN DIEGO
CALIFORNIA
92122

Phone

8582024500

Name of Person for Whose Account the Securities are To Be Sold

Corvex Management LP

See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.

Relationship to Issuer

Affiliate of Director (1)

144: Securities Information

Title of the Class of Securities To Be Sold

Name and Address of the Broker

Number of Shares or Other Units To Be Sold

Aggregate Market Value

Number of Shares or Other Units Outstanding

Approximate Date of Sale

Name the Securities Exchange

Common Stock, par value $0.01 per share

Goldman Sachs & Co. LLC
200 West Street
New York � NY � 10282

600000

87420000.00

151300000

05/13/2026

Nasdaq Stock Market

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class

Date you Acquired

Nature of Acquisition Transaction

Name of Person from Whom Acquired

Is this a Gift?

Date Donor Acquired

Amount of Securities Acquired

Date of Payment

Nature of Payment *

Common Stock, par value $0.01 per share

10/25/2023

Purchases of shares of Common Stock in the open market (2)

Purchases from counterparties in open market transactions

600000

10/25/2023

Cash

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Nothing to Report

144: Remarks and Signature

Remarks

1. Corvex Management LP (Corvex) may be deemed to be the beneficial owner of shares of Common Stock (Common Stock) of Illumina, Inc. (the Issuer) held by one or more funds for which Corvex serves as investment adviser. The general partner of Corvex is controlled by Keith Meister, who serves as a director on the Board of Directors of the Issuer. 2. Shares of Common Stock to be sold were purchased between October 25, 2023 and March 27, 2025 in various open market transactions. In addition, during the previous week, funds for which Corvex serves as investment adviser have terminated equity swaps referencing an aggregate of 344,182 shares of Common Stock that were solely settled in cash.

Date of Notice

05/13/2026

ATTENTION:

The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.

Signature

/s/ Patrick Dooley, authorized signatory of Corvex Management LP

144: Filer Information