144 0001535472 XXXXXXXX LIVE 0001110803 ILLUMINA, INC. 001-35406 5200 ILLUMINA WAY SAN DIEGO CA 92122 8582024500 Corvex Management LP Affiliate of Director (1) Common Stock, par value $0.01 per share Goldman Sachs & Co. LLC

200 West Street New York NY 10282

600000 87420000.00 151300000 05/13/2026 Nasdaq Stock Market Common Stock, par value $0.01 per share 10/25/2023 Purchases of shares of Common Stock in the open market (2) Purchases from counterparties in open market transactions N 600000 10/25/2023 Cash Y 1. Corvex Management LP (Corvex) may be deemed to be the beneficial owner of shares of Common Stock (Common Stock) of Illumina, Inc. (the Issuer) held by one or more funds for which Corvex serves as investment adviser. The general partner of Corvex is controlled by Keith Meister, who serves as a director on the Board of Directors of the Issuer. 2. Shares of Common Stock to be sold were purchased between October 25, 2023 and March 27, 2025 in various open market transactions. In addition, during the previous week, funds for which Corvex serves as investment adviser have terminated equity swaps referencing an aggregate of 344,182 shares of Common Stock that were solely settled in cash. 05/13/2026 /s/ Patrick Dooley, authorized signatory of Corvex Management LP