X0202 SCHEDULE 13G/A 0001169253 XXXXXXXX LIVE 2 Common Shares, no par value 03/31/2026 0001581178 EUPRAXIA PHARMACEUTICALS INC. 29842P105 201-2067 CADBORO BAY RD. VICTORIA BRITISH COLUMBIA A1 V8R 5G4 Rule 13d-1(d) Manchester Management Company, LLC DE 0.00 3830869.00 0.00 3830869.00 3830869.00 N 7.4 OO Manchester Management PR, LLC b PR 0.00 3830869.00 0.00 3830869.00 3830869.00 N 7.4 OO Manchester Explorer, L.P. b DE 0.00 3707942.00 0.00 3707942.00 3707942.00 N 7.1 PN James E. Besser b X1 138293.00 3830869.00 138293.00 3830869.00 3969162.00 N 7.6 IN Morgan C. Frank b X1 307306.00 3707942.00 307306.00 3707942.00 4015248.00 N 7.7 IN EUPRAXIA PHARMACEUTICALS INC. 201-2067 CADBORO BAY RD., VICTORIA, BRITISH COLUMBIA, CANADA, V8R 5G4 MANCHESTER MANAGEMENT COMPANY, LLC MANCHESTER MANAGEMENT PR, LLC MANCHESTER EXPLORER, L.P. JAMES E. BESSER MORGAN C. FRANK MANCHESTER MANAGEMENT COMPANY, LLC 2 Calle Candina, #1701 San Juan, Puerto Rico, 00907 United States of America MANCHESTER MANAGEMENT PR, LLC 2 Calle Candina, #1701 San Juan, Puerto Rico, 00907 United States of America MANCHESTER EXPLORER, L.P. c/o Manchester Management Company, LLC 2 Calle Candina, #1701 San Juan, Puerto Rico, 00907 United States of America JAMES E. BESSER c/o Manchester Management Company, LLC 2 Calle Candina, #1701 San Juan, Puerto Rico, 00907 United States of America MORGAN C. FRANK c/o Manchester Management Company, LLC 2 Calle Candina, #1701 San Juan, Puerto Rico, 00907 United States of America MANCHESTER MANAGEMENT COMPANY, LLC - Delaware MANCHESTER MANAGEMENT PR, LLC - Other - Puerto Rico MANCHESTER EXPLORER, L.P. - Delaware JAMES E. BESSER - United States MORGAN C. FRANK - United States Y MANCHESTER MANAGEMENT COMPANY, LLC - 3,830,869 MANCHESTER MANAGEMENT PR, LLC - 3,830,869 MANCHESTER EXPLORER, L.P. - 3,707,942 JAMES E. BESSER - 3,969,162 MORGAN C. FRANK - 4,015,248 MANCHESTER MANAGEMENT COMPANY, LLC - 7.4% MANCHESTER MANAGEMENT PR, LLC - 7.4% MANCHESTER EXPLORER, L.P. - 7.1% JAMES E. BESSER - 7.6% MORGAN C. FRANK - 7.7% MANCHESTER MANAGEMENT COMPANY, LLC - 0 MANCHESTER MANAGEMENT PR, LLC - 0 MANCHESTER EXPLORER, L.P. - 0 JAMES E. BESSER - 138,293 MORGAN C. FRANK - 307,306 MANCHESTER MANAGEMENT COMPANY, LLC - 3,830,869 MANCHESTER MANAGEMENT PR, LLC - 3,830,869 MANCHESTER EXPLORER, L.P. - 3,707,942 JAMES E. BESSER - 3,830,869 MORGAN C. FRANK - 3,707,942 MANCHESTER MANAGEMENT COMPANY, LLC - 0 MANCHESTER MANAGEMENT PR, LLC - 0 MANCHESTER EXPLORER, L.P. - 0 JAMES E. BESSER - 138,293 MORGAN C. FRANK - 307,306 MANCHESTER MANAGEMENT COMPANY, LLC - 3,830,869 MANCHESTER MANAGEMENT PR, LLC - 3,830,869 MANCHESTER EXPLORER, L.P. - 3,707,942 JAMES E. BESSER - 3,830,869 MORGAN C. FRANK - 3,707,942 Y N All of the securities reported in this Schedule 13G, other than those securities reported herein that James E. Besser and Morgan C. Frank have the sole power to vote, direct the vote, dispose of or direct the disposition of, are directly owned by advisory clients of Manchester Management PR, LLC. None of those advisory clients, other than Manchester Explorer, L.P., may be deemed to beneficially own more than 5% of the Common Shares, no par value. Y Y Y Y Exhibit A - Joint Filing Agreement Manchester Management Company, LLC /s/ James E. Besser 05/12/2026 Manchester Management PR, LLC /s/ James E. Besser 05/12/2026 Manchester Explorer, L.P. /s/ James E. Besser 05/12/2026 James E. Besser /s/ James E. Besser 05/12/2026 Morgan C. Frank /s/ James E. Besser 05/12/2026