144 0001697362 XXXXXXXX LIVE 0001604821 NATERA, INC. 001-37478 13011 McCallen Pass, Bldg A Suite 100 Austin TX 78753 6509809190 MICHAEL BROPHY Officer Common Morgan Stanley Smith Barney LLC Executive Financial Services

1 New York Plaza 8th Floor New York NY 10004

3070 614521.90 141731250 04/29/2026 NASDAQ Common 04/26/2026 Restricted Stock Units Issuer N 3070 04/26/2026 N/A N MICHAEL BURKES BROPHY

13011 McCallen Pass, Bldg A Suite 100 Austin TX 78753

Common 03/10/2026 785 160244.17 10b5-1 Sales Plan for MICHAEL BROPHY

13011 McCallen Pass, Bldg A Suite 100 Austin TX 78753

Common 02/03/2026 5671 1288312.83 The securities to be sold were acquired upon the vesting of restricted stock units during the period of 4/26/2026 through 4/27/2026 04/29/2026 09/10/2025 /s/ Michael Burkes Brophy