X0609 4 2022-08-02 0001735438 MeiraGTx Holdings plc MGTX 0001224962 PERCEPTIVE ADVISORS LLC false 51 ASTOR PLACE, 10TH FLOOR NEW YORK NY 10003 true false true false 0001164426 EDELMAN JOSEPH false 51 ASTOR PLACE, 10TH FLOOR NEW YORK NY 10003 true false true false 0001249675 PERCEPTIVE LIFE SCIENCES MASTER FUND LTD false 51 ASTOR PLACE, 10TH FLOOR NEW YORK NY 10003 true false true false false Ordinary Shares 2026-04-17 4 A false 555555 9.00 A 10786658 I See Footnote Warrant (Right to Buy) 15.00 2022-08-02 4 A false 400000 A 2022-08-02 2027-08-02 Ordinary Shares 400000 400000 I See Footnote Warrant (Right to Buy) 20.00 2022-08-02 4 A false 300000 A 2022-08-02 2027-08-02 Ordinary Shares 300000 300000 I See Footnote Warrant (Right to Buy) 15.00 2026-03-25 4 D false 400000 D 2022-08-02 2027-08-02 Ordinary Shares 400000 0 I See Footnote Warrant (Right to Buy) 20.00 2026-03-25 4 D false 300000 D 2022-08-02 2027-08-02 Ordinary Shares 300000 0 I See Footnote Warrant (Right to Buy) 8.00 2026-03-25 4 A false 400000 A 2026-03-25 2027-08-02 Ordinary Shares 400000 400000 I See Footnote Warrant (Right to Buy) 8.00 2026-03-25 4 A false 300000 A 2026-03-25 2027-08-02 Ordinary Shares 300000 300000 I See Footnote The securities are directly held by Perceptive Life Sciences Master Fund Ltd. (the "Master Fund"). Perceptive Advisors LLC (the "Advisor") serves as the investment manager of Master Fund. Joseph Edelman is the managing member of the Advisor. Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes. Issued to Perceptive Credit Holdings III, LP ("Credit Fund III") in connection with the senior secured financing arrangement (the "Financing Agreement") by and among the Issuer, PCH III, and the other parties thereto. Perceptive Credit Advisors LLC ("Perceptive Credit Advisors") serves as the investment advisor to Credit Fund III and as a relying advisor under the Advisor. Mr. Edelman is the managing member of Perceptive Credit Advisors. Each of Perceptive Credit Advisors, the Advisor and Mr. Edelman disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that any of Perceptive Credit Advisors, the Advisor and Mr. Edelman is the beneficial owner of such securities for purposes of Section 16 or for any other purposes. On March 25, 2026, the Issuer, Credit Fund III, and the other parties to the Financing Agreement entered into an agreement whereby the exercise price of the warrants was adjusted to $8.00 per share. Ellen Hukkelhoven, the Head of Investment Research of the Advisor, is a member of the Issuer's board of directors. /s/ Perceptive Advisors LLC, By: Joseph Edelman, its managing member 2026-04-23 /s/ Joseph Edelman - for Perceptive Life Sciences Master Fund Ltd., By: Perceptive Advisors LLC, its investment manager, By: Joseph Edelman, its managing member 2026-04-23 /s/ Joseph Edelman 2026-04-23