v3.26.1
Pay vs Performance Disclosure - USD ($)
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Pay vs Performance Disclosure        
Pay vs Performance Disclosure, Table
Year
(1)
Summary
Compensation
table total for
PEO
(1)(2)
Compensation
actually paid
to PEO
(1)
Average
summary
Compensation
table total for
non-PEO
NEOs
(1)(2)
Average
Compensation
actually paid
to non-PEO
NEOs
Value of initial fixed
$100 investment
based on:
(3)
Company
TSR
(3)
Peer
Group TSR
Net Loss
(in thousands)
Revenue (in
thousands)
2025
$ 7,712,736 $ 34,945,674 $ 2,806,280 $ 12,084,939 $ 708.21 $ 120.69 $ (68,924) $ 158,320
2024
$ 6,751,230 $ 6,236,714 $ 3,323,681 $ 3,129,713 $ 241.48 $ 91.15 $ (130,394) $ 13,996
2023
$ 4,889,498 $ 15,455,856 $ 2,244,223 $ 4,823,625 $ 247.02 $ 92.42 $ (78,502) $ 17,488
2022
$ 10,762,132 $ 13,888,510 $ 1,763,908 $ 2,177,710 $ 130.80 $ 89.09 $ (41,015) $ 15,935
(1)   For each fiscal year, represents amount reported for our PEO and average amount reported for our NEOs, in each case in the Total column of the Summary of Compensation Table. Our PEO and NEOs for each of these fiscal years are shown below:
Year
PEO
Non-PEO NEOs
2025
Roger A. Jeffs, Ph.D.
Michael Kaseta, Russell Schundler,
Rajeev Saggar, M.D., Scott Moomaw
2024
Roger A. Jeffs, Ph.D.
Michael Kaseta, Russell Schundler
2023
Roger A. Jeffs, Ph.D.
Michael Kaseta, Russell Schundler
Year
PEO
Non-PEO NEOs
2022
Roger A. Jeffs, Ph.D.
Michael Kaseta, Russell Schundler
(2)   Amounts represent Compensation Actually Paid to our PEO and the average Compensation Actually Paid to our non-PEO NEOs for the relevant fiscal year. Compensation Actually Paid represents the amount reported in the Total column of the Summary Compensation Table for the applicable fiscal year, adjusted as shown below. Fair value or change in fair value, as applicable, of equity awards in the Compensation Actually Paid columns was determined as follows: (i) the fair value as of the end of the fiscal year of outstanding and unvested equity awards granted in that year; (ii) the change in fair value during the year of equity awards granted in prior years that remained outstanding and unvested at the end of the year; (iii) the fair value as of the vesting date of equity awards that were granted and vested in that year; and (iv) the change in fair value during the year through the vesting date of equity awards granted in prior years that vested during that year. Equity values are calculated in accordance with ASC Topic 718.
Year
Reported Summary
Compensation Table
Total for Dr. Jeffs
(a)
Reported Value of
Equity Awards for
Dr. Jeffs
(b)
Aggregate Equity
Award Adjustments
for Dr. Jeffs
Compensation
Actually Paid to
Dr. Jeffs
2025
$ 7,712,736 $ (5,590,992) $ 32,823,930
$
34,945,674
2024
$ 6,751,230 $ (5,533,450) $ 5,018,934
$
6,236,714
2023
$ 4,889,498 $ (3,566,418) $ 14,132,776
$
15,455,856
2022
$ 10,762,132 $ (10,229,906) $ 13,356,284
$
13,888,510
(a)   Represents the reported value of equity awards as reported in the “Stock Awards” and “Option Awards” columns in the Summary Compensation Table for the applicable year.
(b)   The amounts deducted or added in calculating the equity award adjustments are as follows:
Year
Year-End Fair
Value of Equity
Awards Granted
During Year
That
Remained
Unvested as of
Last Day of Year
for Dr. Jeffs
Change in
Fair Value
from Last
Day of Prior
Year to Last
Day of Year
of Unvested
Equity
Awards for
Dr. Jeffs
Vesting-Date
Fair Value of
Equity Awards
Granted
During Year
that Vested
During Year
for Dr. Jeffs
Change in
Fair Value
from Last
Day of
Prior Year
to Vesting
Date of
Unvested
Equity
Awards
that Vested
During
Year for
Dr. Jeffs
Fair Value at
Last Day of
Prior Year of
Equity
Awards
Failed to
Meet Vesting
Conditions
During Year
for Dr. Jeffs
Dollar Value
of any
Dividends or
Other
Earnings Paid
on Stock or
Option
Awards
During Year
Prior to the
Vesting Date
that are not
otherwise
included in the
Total
Compensation
During Year
for Dr. Jeffs
Aggregate
Equity
Awards
Adjustment
2025
$ 15,818,976 $ 11,071,066 $  —
$
5,933,888
$  — $  — $ 32,823,930
Year
Average Reported
Summary
Compensation
Table Total for
non-PEO NEOs
(a)
Average Reported
Value of Equity
Awards for
non-PEO NEOs
(b)
Average Aggregate
Equity Award
Adjustments for
non-PEO NEOs
Average
Compensation
Actually Paid
to non-PEO
NEOs
2025
$ 2,806,280 $ (1,853,019) $ 11,131,678 $ 12,084,939
2024
$ 3,323,681 $ (2,540,813) $ 2,346,845 $ 3,129,713
2023
$ 2,244,223 $ (1,409,527) $ 3,988,929 $ 4,823,625
2022
$ 1,763,908 $ (1,179,023) $ 1,592,825 $ 2,177,710
(a)   Represents the reported value of equity awards as reported in the “Stock Awards” and “Option Awards” columns in the Summary Compensation Table for the applicable year.
(b)   The amounts deducted or added in calculating the equity award adjustments are as follows:
Year
Year-End
Fair
Value of
Equity
Awards
Granted
During
Year That
Remained
Unvested as of
Last Day of
Year for
non-PEO
NEOs
Change in
Fair
Value
from Last
Day of Prior
Year to
Last Day
of Year of
Unvested Equity
Awards for
non-PEO
NEOs
Vesting-Date
Fair Value of
Equity Awards
Granted During
Year that
Vested During
Year for
non-PEO
NEOs
Change in
Fair Value
from
Last Day
of Prior Year
to Vesting
Date of
Unvested
Equity
Awards that
Vested
During
Year for
non-PEO
NEOs
Fair Value
at Last
Day of
Prior Year
of Equity
Awards
Failed to
Meet
Vesting
Conditions
During
Year for
non-PEO
NEOs
Dollar
Value of
any
Dividends
or Other
Earnings
Paid on
Stock or
Option
Awards
During
Year Prior
to the
Vesting
Date that
are not
otherwise
included in
the Total
Compensation
During
Year for
non-PEO
NEOs
Average
Aggregate
Equity
Awards
Adjustment
2025
$ 6,153,861 $ 3,941,821 $
$
1,035,996
$ $ $ 11,131,678
(3)   For the relevant fiscal year, represents the cumulative TSR of our common stock and our Peer Group at the end of each fiscal year. In each case, assume an initial investment of $100 on December 31, 2022. The Peer Group reflects the Nasdaq Biotechnology Index, which is the same industry peer group used in the stock performance graph required by Item 201(e) of Regulation S-K and included in our Annual Report.
     
Company Selected Measure Name Revenue      
Named Executive Officers, Footnote
(1)   For each fiscal year, represents amount reported for our PEO and average amount reported for our NEOs, in each case in the Total column of the Summary of Compensation Table. Our PEO and NEOs for each of these fiscal years are shown below:
Year
PEO
Non-PEO NEOs
2025
Roger A. Jeffs, Ph.D.
Michael Kaseta, Russell Schundler,
Rajeev Saggar, M.D., Scott Moomaw
2024
Roger A. Jeffs, Ph.D.
Michael Kaseta, Russell Schundler
2023
Roger A. Jeffs, Ph.D.
Michael Kaseta, Russell Schundler
Year
PEO
Non-PEO NEOs
2022
Roger A. Jeffs, Ph.D.
Michael Kaseta, Russell Schundler
     
Peer Group Issuers, Footnote
(3)   For the relevant fiscal year, represents the cumulative TSR of our common stock and our Peer Group at the end of each fiscal year. In each case, assume an initial investment of $100 on December 31, 2022. The Peer Group reflects the Nasdaq Biotechnology Index, which is the same industry peer group used in the stock performance graph required by Item 201(e) of Regulation S-K and included in our Annual Report.
     
PEO Total Compensation Amount $ 7,712,736 $ 6,751,230 $ 4,889,498 $ 10,762,132
PEO Actually Paid Compensation Amount $ 34,945,674 6,236,714 15,455,856 13,888,510
Adjustment To PEO Compensation, Footnote
(2)   Amounts represent Compensation Actually Paid to our PEO and the average Compensation Actually Paid to our non-PEO NEOs for the relevant fiscal year. Compensation Actually Paid represents the amount reported in the Total column of the Summary Compensation Table for the applicable fiscal year, adjusted as shown below. Fair value or change in fair value, as applicable, of equity awards in the Compensation Actually Paid columns was determined as follows: (i) the fair value as of the end of the fiscal year of outstanding and unvested equity awards granted in that year; (ii) the change in fair value during the year of equity awards granted in prior years that remained outstanding and unvested at the end of the year; (iii) the fair value as of the vesting date of equity awards that were granted and vested in that year; and (iv) the change in fair value during the year through the vesting date of equity awards granted in prior years that vested during that year. Equity values are calculated in accordance with ASC Topic 718.
Year
Reported Summary
Compensation Table
Total for Dr. Jeffs
(a)
Reported Value of
Equity Awards for
Dr. Jeffs
(b)
Aggregate Equity
Award Adjustments
for Dr. Jeffs
Compensation
Actually Paid to
Dr. Jeffs
2025
$ 7,712,736 $ (5,590,992) $ 32,823,930
$
34,945,674
2024
$ 6,751,230 $ (5,533,450) $ 5,018,934
$
6,236,714
2023
$ 4,889,498 $ (3,566,418) $ 14,132,776
$
15,455,856
2022
$ 10,762,132 $ (10,229,906) $ 13,356,284
$
13,888,510
(a)   Represents the reported value of equity awards as reported in the “Stock Awards” and “Option Awards” columns in the Summary Compensation Table for the applicable year.
(b)   The amounts deducted or added in calculating the equity award adjustments are as follows:
Year
Year-End Fair
Value of Equity
Awards Granted
During Year
That
Remained
Unvested as of
Last Day of Year
for Dr. Jeffs
Change in
Fair Value
from Last
Day of Prior
Year to Last
Day of Year
of Unvested
Equity
Awards for
Dr. Jeffs
Vesting-Date
Fair Value of
Equity Awards
Granted
During Year
that Vested
During Year
for Dr. Jeffs
Change in
Fair Value
from Last
Day of
Prior Year
to Vesting
Date of
Unvested
Equity
Awards
that Vested
During
Year for
Dr. Jeffs
Fair Value at
Last Day of
Prior Year of
Equity
Awards
Failed to
Meet Vesting
Conditions
During Year
for Dr. Jeffs
Dollar Value
of any
Dividends or
Other
Earnings Paid
on Stock or
Option
Awards
During Year
Prior to the
Vesting Date
that are not
otherwise
included in the
Total
Compensation
During Year
for Dr. Jeffs
Aggregate
Equity
Awards
Adjustment
2025
$ 15,818,976 $ 11,071,066 $  —
$
5,933,888
$  — $  — $ 32,823,930
     
Non-PEO NEO Average Total Compensation Amount $ 2,806,280 3,323,681 2,244,223 1,763,908
Non-PEO NEO Average Compensation Actually Paid Amount $ 12,084,939 3,129,713 4,823,625 2,177,710
Adjustment to Non-PEO NEO Compensation Footnote
(2)   Amounts represent Compensation Actually Paid to our PEO and the average Compensation Actually Paid to our non-PEO NEOs for the relevant fiscal year. Compensation Actually Paid represents the amount reported in the Total column of the Summary Compensation Table for the applicable fiscal year, adjusted as shown below. Fair value or change in fair value, as applicable, of equity awards in the Compensation Actually Paid columns was determined as follows: (i) the fair value as of the end of the fiscal year of outstanding and unvested equity awards granted in that year; (ii) the change in fair value during the year of equity awards granted in prior years that remained outstanding and unvested at the end of the year; (iii) the fair value as of the vesting date of equity awards that were granted and vested in that year; and (iv) the change in fair value during the year through the vesting date of equity awards granted in prior years that vested during that year. Equity values are calculated in accordance with ASC Topic 718.
Year
Average Reported
Summary
Compensation
Table Total for
non-PEO NEOs
(a)
Average Reported
Value of Equity
Awards for
non-PEO NEOs
(b)
Average Aggregate
Equity Award
Adjustments for
non-PEO NEOs
Average
Compensation
Actually Paid
to non-PEO
NEOs
2025
$ 2,806,280 $ (1,853,019) $ 11,131,678 $ 12,084,939
2024
$ 3,323,681 $ (2,540,813) $ 2,346,845 $ 3,129,713
2023
$ 2,244,223 $ (1,409,527) $ 3,988,929 $ 4,823,625
2022
$ 1,763,908 $ (1,179,023) $ 1,592,825 $ 2,177,710
(a)   Represents the reported value of equity awards as reported in the “Stock Awards” and “Option Awards” columns in the Summary Compensation Table for the applicable year.
(b)   The amounts deducted or added in calculating the equity award adjustments are as follows:
Year
Year-End
Fair
Value of
Equity
Awards
Granted
During
Year That
Remained
Unvested as of
Last Day of
Year for
non-PEO
NEOs
Change in
Fair
Value
from Last
Day of Prior
Year to
Last Day
of Year of
Unvested Equity
Awards for
non-PEO
NEOs
Vesting-Date
Fair Value of
Equity Awards
Granted During
Year that
Vested During
Year for
non-PEO
NEOs
Change in
Fair Value
from
Last Day
of Prior Year
to Vesting
Date of
Unvested
Equity
Awards that
Vested
During
Year for
non-PEO
NEOs
Fair Value
at Last
Day of
Prior Year
of Equity
Awards
Failed to
Meet
Vesting
Conditions
During
Year for
non-PEO
NEOs
Dollar
Value of
any
Dividends
or Other
Earnings
Paid on
Stock or
Option
Awards
During
Year Prior
to the
Vesting
Date that
are not
otherwise
included in
the Total
Compensation
During
Year for
non-PEO
NEOs
Average
Aggregate
Equity
Awards
Adjustment
2025
$ 6,153,861 $ 3,941,821 $
$
1,035,996
$ $ $ 11,131,678
     
Compensation Actually Paid vs. Total Shareholder Return [MISSING IMAGE: bc_comppaidvstsr-4c.jpg]      
Compensation Actually Paid vs. Net Income
[MISSING IMAGE: bc_comppaidvsnetloss-4c.jpg]
     
Compensation Actually Paid vs. Company Selected Measure [MISSING IMAGE: bc_comppaidvsrevenue-4c.jpg]      
Total Shareholder Return Vs Peer Group [MISSING IMAGE: bc_comppaidvstsr-4c.jpg]      
Total Shareholder Return Amount $ 708.21 241.48 247.02 130.8
Peer Group Total Shareholder Return Amount 120.69 91.15 92.42 89.09
Net Income (Loss) $ (68,924,000) $ (130,394,000) $ (78,502,000) $ (41,015,000)
Company Selected Measure Amount 158,320,000 13,996,000 17,488,000 15,935,000
PEO Name Roger A. Jeffs, Ph.D      
Equity Awards Adjustments, Footnote The amounts deducted or added in calculating the equity award adjustments are as follows:
Year
Year-End Fair
Value of Equity
Awards Granted
During Year
That
Remained
Unvested as of
Last Day of Year
for Dr. Jeffs
Change in
Fair Value
from Last
Day of Prior
Year to Last
Day of Year
of Unvested
Equity
Awards for
Dr. Jeffs
Vesting-Date
Fair Value of
Equity Awards
Granted
During Year
that Vested
During Year
for Dr. Jeffs
Change in
Fair Value
from Last
Day of
Prior Year
to Vesting
Date of
Unvested
Equity
Awards
that Vested
During
Year for
Dr. Jeffs
Fair Value at
Last Day of
Prior Year of
Equity
Awards
Failed to
Meet Vesting
Conditions
During Year
for Dr. Jeffs
Dollar Value
of any
Dividends or
Other
Earnings Paid
on Stock or
Option
Awards
During Year
Prior to the
Vesting Date
that are not
otherwise
included in the
Total
Compensation
During Year
for Dr. Jeffs
Aggregate
Equity
Awards
Adjustment
2025
$ 15,818,976 $ 11,071,066 $  —
$
5,933,888
$  — $  — $ 32,823,930
The amounts deducted or added in calculating the equity award adjustments are as follows:
Year
Year-End
Fair
Value of
Equity
Awards
Granted
During
Year That
Remained
Unvested as of
Last Day of
Year for
non-PEO
NEOs
Change in
Fair
Value
from Last
Day of Prior
Year to
Last Day
of Year of
Unvested Equity
Awards for
non-PEO
NEOs
Vesting-Date
Fair Value of
Equity Awards
Granted During
Year that
Vested During
Year for
non-PEO
NEOs
Change in
Fair Value
from
Last Day
of Prior Year
to Vesting
Date of
Unvested
Equity
Awards that
Vested
During
Year for
non-PEO
NEOs
Fair Value
at Last
Day of
Prior Year
of Equity
Awards
Failed to
Meet
Vesting
Conditions
During
Year for
non-PEO
NEOs
Dollar
Value of
any
Dividends
or Other
Earnings
Paid on
Stock or
Option
Awards
During
Year Prior
to the
Vesting
Date that
are not
otherwise
included in
the Total
Compensation
During
Year for
non-PEO
NEOs
Average
Aggregate
Equity
Awards
Adjustment
2025
$ 6,153,861 $ 3,941,821 $
$
1,035,996
$ $ $ 11,131,678
     
PEO | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount $ (5,590,992) $ (5,533,450) $ (3,566,418) $ (10,229,906)
PEO | Equity Awards Adjustments, Excluding Value Reported in Compensation Table        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount 32,823,930 5,018,934 14,132,776 13,356,284
PEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount 15,818,976      
PEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount 11,071,066      
PEO | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount      
PEO | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount 5,933,888      
PEO | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount      
PEO | Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount      
Non-PEO NEO | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount (1,853,019) (2,540,813) (1,409,527) (1,179,023)
Non-PEO NEO | Equity Awards Adjustments, Excluding Value Reported in Compensation Table        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount 11,131,678 $ 2,346,845 $ 3,988,929 $ 1,592,825
Non-PEO NEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount 6,153,861      
Non-PEO NEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount 3,941,821      
Non-PEO NEO | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount      
Non-PEO NEO | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount 1,035,996      
Non-PEO NEO | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount      
Non-PEO NEO | Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year        
Pay vs Performance Disclosure        
Adjustment to Compensation, Amount