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New hire equity awards are granted on a new hire’s employment start date. Neither the Board nor the Compensation Committee take into account material non-public information when determining the timing or terms of stock option awards, nor do we time disclosure of material non-public information for the purpose of affecting the value of executive compensation. The Compensation Committee has also authorized the Company’s CEO to approve spot grants to reward employees (not including executive officers) for exceptional performance from time to time, subject to annual limits. </span> </div><div style="text-indent:20pt; margin-top:8pt; text-align:justify; width:456pt; line-height:12pt;"> <span style="letter-spacing:0.2pt;">In response to Item 402(x), during 2025, we did not grant stock options (or similar awards) to any NEO during any period beginning four business days before and ending one business day after the filing of any company periodic report on Form 10-Q or Form 10-K, or the filing or furnishing of any Company Form 8-K that disclosed any material non-public information. </span> </div> Under our practices, our Compensation Committee grants equity awards in the first quarter of each fiscal year to the Company’s executive officers and employees and grants equity awards to independent members of the Board of Directors after each annual meeting of stockholders. New hire equity awards are granted on a new hire’s employment start date. Neither the Board nor the Compensation Committee take into account material non-public information when determining the timing or terms of stock option awards, nor do we time disclosure of material non-public information for the purpose of affecting the value of executive compensation. Neither the Board nor the Compensation Committee take into account material non-public information when determining the timing or terms of stock option awards, nor do we time disclosure of material non-public information for the purpose of affecting the value of executive compensation. true false false <table style="width:456pt;height:122.5pt;margin-top:10pt;border-collapse: collapse;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <tr style="line-height:9pt;height:31.75pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td rowspan="2" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:61.51pt;text-align:left;"> <div style="white-space:nowrap; line-height:9pt; padding-bottom:0.333333333333333pt;"> <span style="letter-spacing:-0.16pt;">Year </span> </div> </td> <td rowspan="2" style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td rowspan="2" style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" rowspan="2" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center; line-height:9pt; padding-bottom:0.333333333333333pt;"> <span style="letter-spacing:-0.16pt;">(1) <br/> Summary <br/> Compensation <br/> table total for <br/> PEO </span> </div> </td> <td rowspan="2" style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td rowspan="2" style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" rowspan="2" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center; line-height:9pt; padding-bottom:0.333333333333333pt;"> <span style="letter-spacing:-0.16pt;">(1)(2) <br/> Compensation <br/> actually paid <br/> to PEO </span> </div> </td> <td rowspan="2" style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td rowspan="2" style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" rowspan="2" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center; line-height:9pt; padding-bottom:0.333333333333333pt;"> <span style="letter-spacing:-0.16pt;">(1) <br/> Average <br/> summary <br/> Compensation <br/> table total for <br/> non-PEO <br/> NEOs </span> </div> </td> <td rowspan="2" style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td rowspan="2" style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" rowspan="2" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center; line-height:9pt; padding-bottom:0.333333333333333pt;"> <span style="letter-spacing:-0.16pt;">(1)(2) <br/> Average <br/> Compensation <br/> actually paid <br/> to non-PEO <br/> NEOs </span> </div> </td> <td rowspan="2" style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="10" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Value of initial fixed <br/> $100 investment <br/> based on: </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="6">​</td> <td colspan="6">​</td> </tr> <tr style="line-height:9pt;height:31.5pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:2.583pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">(3) <br/> Company <br/> TSR </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:2.583pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">(3) <br/> Peer <br/> Group TSR </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:2.583pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Net Loss <br/> (in thousands) </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:2.583pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Revenue (in <br/> thousands) </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.25pt 0pt 1.5pt 0pt; width:61.51pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">7,712,736</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">34,945,674</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0.960000000000001pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">2,806,280</td> <td style="padding:0pt;padding-left:0.960000000000001pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">12,084,939</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:21pt; text-align:right; white-space:nowrap;">708.21</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:3.11pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:21pt; text-align:right; white-space:nowrap;">120.69</td> <td style="padding:0pt;padding-left:3.11pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:2.635pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">(68,924<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:2.635pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0.125pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:24.75pt; text-align:right; white-space:nowrap;">158,320</td> <td style="padding:0pt;padding-left:0.125pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:61.51pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2024 </span> </div> </td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">6,751,230</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">6,236,714</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0.960000000000001pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">3,323,681</td> <td style="padding:0pt;padding-left:0.960000000000001pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">3,129,713</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:21pt; text-align:right; white-space:nowrap;">241.48</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:3.11pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:21pt; text-align:right; white-space:nowrap;">91.15</td> <td style="padding:0pt;padding-left:3.11pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:2.635pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">(130,394<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:2.635pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0.125pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:24.75pt; text-align:right; white-space:nowrap;">13,996</td> <td style="padding:0pt;padding-left:0.125pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:61.51pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2023 </span> </div> </td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">4,889,498</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">15,455,856</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0.960000000000001pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">2,244,223</td> <td style="padding:0pt;padding-left:0.960000000000001pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">4,823,625</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:21pt; text-align:right; white-space:nowrap;">247.02</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:3.11pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:21pt; text-align:right; white-space:nowrap;">92.42</td> <td style="padding:0pt;padding-left:3.11pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:2.635pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">(78,502<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:2.635pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0.125pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:24.75pt; text-align:right; white-space:nowrap;">17,488</td> <td style="padding:0pt;padding-left:0.125pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:61.51pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2022 </span> </div> </td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">10,762,132</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">13,888,510</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0.960000000000001pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">1,763,908</td> <td style="padding:0pt;padding-left:0.960000000000001pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">2,177,710</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:21pt; text-align:right; white-space:nowrap;">130.80</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:3.11pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:21pt; text-align:right; white-space:nowrap;">89.09</td> <td style="padding:0pt;padding-left:3.11pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:2.635pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">(41,015<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:2.635pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0.125pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:24.75pt; text-align:right; white-space:nowrap;">15,935</td> <td style="padding:0pt;padding-left:0.125pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> </table><div style="margin-left: 0pt; width: 108pt; margin-top: 0pt; font-size: 1pt; line-height: 0pt; border-bottom: 1pt solid #000000; ">​</div><div style="margin-top:6pt; text-align:justify; width:456pt; line-height:12pt;"> <span style=" position:relative; bottom:4.25pt;font-size:7.5pt;letter-spacing:0.15pt;">(1)</span><span style="letter-spacing:0.2pt;">   For each fiscal year, represents amount reported for our PEO and average amount reported for our NEOs, in each case in the Total column of the Summary of Compensation Table. Our PEO and NEOs for each of these fiscal years are shown below: </span> </div><table style="width:416pt;height:65.5pt;margin-left:20pt;margin-top:10pt;border-collapse: collapse;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <tr style="line-height:8pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.5pt 0pt; width:145.28pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Year </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.5pt 0pt; width:88.7pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:-0.16pt;">PEO </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.5pt 0pt; width:158.02pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:-0.16pt;">Non-PEO NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;">​</td> </tr> <tr style="line-height:12pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:top;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:1.917pt 0pt 0.5pt 0pt; width:145.28pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:1.917pt 0pt 0.5pt 0pt; width:88.7pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:0.2pt;">Roger A. Jeffs, Ph.D. </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:1.917pt 0pt 0.5pt 0pt; width:158.02pt;"> <div style="text-align:center;"> <span style="letter-spacing:0.2pt;">Michael Kaseta, Russell Schundler, <br/> Rajeev Saggar, M.D., Scott Moomaw </span> </div> </td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;white-space:nowrap;text-align:center;vertical-align:top;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 0.5pt 0pt; width:145.28pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2024 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:3.5pt 0pt 0.5pt 0pt; width:88.7pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:0.2pt;">Roger A. Jeffs, Ph.D. </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:3.5pt 0pt 0.5pt 0pt; width:158.02pt;"> <div style="text-align:center;"> <span style="letter-spacing:0.2pt;">Michael Kaseta, Russell Schundler </span> </div> </td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:top;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 0.5pt 0pt; width:145.28pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2023 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:3.5pt 0pt 0.5pt 0pt; width:88.7pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:0.2pt;">Roger A. Jeffs, Ph.D. </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:3.5pt 0pt 0.5pt 0pt; width:158.02pt;"> <div style="text-align:center;"> <span style="letter-spacing:0.2pt;">Michael Kaseta, Russell Schundler </span> </div> </td> <td style="padding:0pt; width:0pt;">​</td> </tr> </table><table style="width:416pt;height:23.5pt;margin-left:20pt;margin-top:0pt;border-collapse: collapse;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <tr style="line-height:8pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.5pt 0pt; width:145.28pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Year </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.5pt 0pt; width:88.7pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:-0.16pt;">PEO </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.5pt 0pt; width:158.02pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:-0.16pt;">Non-PEO NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:top;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.25pt 0pt 2.5pt 0pt; width:145.28pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2022 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:3.25pt 0pt 2.5pt 0pt; width:88.7pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:0.2pt;">Roger A. Jeffs, Ph.D. </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:3.25pt 0pt 2.5pt 0pt; width:158.02pt;"> <div style="text-align:center;"> <span style="letter-spacing:0.2pt;">Michael Kaseta, Russell Schundler</span> </div> </td> <td style="padding:0pt; width:0pt;">​</td> </tr> </table><div style="margin-top:10pt; text-align:justify; width:456pt; line-height:12pt;font-weight:normal;font-size:10pt;"> <span style=" position:relative; bottom:4.25pt;font-size:7.5pt;letter-spacing:0.15pt;">(2)</span><span style="letter-spacing:0.2pt;">   Amounts represent Compensation Actually Paid to our PEO and the average Compensation Actually Paid to our non-PEO NEOs for the relevant fiscal year. Compensation Actually Paid represents the amount reported in the Total column of the Summary Compensation Table for the applicable fiscal year, adjusted as shown below. Fair value or change in fair value, as applicable, of equity awards in the Compensation Actually Paid columns was determined as follows: (i) the fair value as of the end of the fiscal year of outstanding and unvested equity awards granted in that year; (ii) the change in fair value during the year of equity awards granted in prior years that remained outstanding and unvested at the end of the year; (iii) the fair value as of the vesting date of equity awards that were granted and vested in that year; and (iv) the change in fair value during the year through the vesting date of equity awards granted in prior years that vested during that year. Equity values are calculated in accordance with ASC Topic 718. </span> </div><table style="width:416pt;height:95.5pt;margin-left:20pt;margin-top:10pt;border-collapse: collapse;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <tr style="line-height:9pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:121.41pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Year </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Reported Summary <br/> Compensation Table <br/> Total for Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">(a) <br/> Reported Value of <br/> Equity Awards for <br/> Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">(b) <br/> Aggregate Equity <br/> Award Adjustments <br/> for Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Compensation <br/> Actually Paid to <br/> Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.25pt 0pt 1.5pt 0pt; width:121.41pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:8.765pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">7,712,736</td> <td style="padding:0pt;padding-left:8.765pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:3.165pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:36.75pt; text-align:right; white-space:nowrap;">(5,590,992<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:3.165pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.96pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">32,823,930</td> <td style="padding:0pt;padding-left:6.96pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:1.92pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; "> <div style="font-weight:bold;">$</div> </td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;"> <div style="font-weight:bold;"> <span style="font-weight:normal;">34,945,674</span> </div> </td> <td style="padding:0pt;padding-left:1.92pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:121.41pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2024 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:8.765pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">6,751,230</td> <td style="padding:0pt;padding-left:8.765pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:3.165pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:36.75pt; text-align:right; white-space:nowrap;">(5,533,450<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:3.165pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.96pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">5,018,934</td> <td style="padding:0pt;padding-left:6.96pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:1.92pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; "> <div style="font-weight:bold;">$</div> </td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;"> <div style="font-weight:bold;"> <span style="font-weight:normal;">6,236,714</span> </div> </td> <td style="padding:0pt;padding-left:1.92pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:121.41pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2023 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:8.765pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">4,889,498</td> <td style="padding:0pt;padding-left:8.765pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:3.165pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:36.75pt; text-align:right; white-space:nowrap;">(3,566,418<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:3.165pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.96pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">14,132,776</td> <td style="padding:0pt;padding-left:6.96pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:1.92pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; "> <div style="font-weight:bold;">$</div> </td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;"> <div style="font-weight:bold;"> <span style="font-weight:normal;">15,455,856</span> </div> </td> <td style="padding:0pt;padding-left:1.92pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:121.41pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2022 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:8.765pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">10,762,132</td> <td style="padding:0pt;padding-left:8.765pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:3.165pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:36.75pt; text-align:right; white-space:nowrap;">(10,229,906<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:3.165pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.96pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">13,356,284</td> <td style="padding:0pt;padding-left:6.96pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:1.92pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; "> <div style="font-weight:bold;">$</div> </td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;"> <div style="font-weight:bold;"> <span style="font-weight:normal;">13,888,510</span> </div> </td> <td style="padding:0pt;padding-left:1.92pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> </table><div style="margin-left: 0pt; width: 108pt; margin-top: 0pt; font-size: 1pt; line-height: 0pt; border-bottom: 1pt solid #000000; ">​</div><div style="margin-left:20pt; margin-top:6pt; text-align:justify; width:436pt; line-height:12pt;font-weight:normal;font-size:10pt;"> <span style=" position:relative; bottom:4.25pt;font-size:7.5pt;letter-spacing:0.15pt;">(a)</span><span style="letter-spacing:0.2pt;">   Represents the reported value of equity awards as reported in the “Stock Awards” and “Option Awards” columns in the Summary Compensation Table for the applicable year. </span> </div><div style="margin-left:20pt; margin-top:6pt; text-align:justify; width:436pt; line-height:9.5pt;font-weight:normal;font-size:10pt;"> <span style=" position:relative; bottom:4.25pt;font-size:7.5pt;letter-spacing:0.15pt;">(b)</span><span style="letter-spacing:0.2pt;">   The amounts deducted or added in calculating the equity award adjustments are as follows: </span> </div><table style="width:416pt;height:176.5pt;margin-left:20pt;margin-top:10pt;border-collapse: collapse;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <tr style="line-height:9pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:36.74pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Year </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Year-End Fair <br/> Value of Equity <br/> Awards Granted <br/> During Year <br/> That <br/> Remained <br/> Unvested as of <br/> Last Day of Year <br/> for Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Change in <br/> Fair Value <br/> from Last <br/> Day of Prior <br/> Year to Last <br/> Day of Year <br/> of Unvested <br/> Equity <br/> Awards for <br/> Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Vesting-Date <br/> Fair Value of <br/> Equity Awards <br/> Granted <br/> During Year <br/> that Vested <br/> During Year <br/> for Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Change in <br/> Fair Value <br/> from Last <br/> Day of <br/> Prior Year <br/> to Vesting <br/> Date of <br/> Unvested <br/> Equity <br/> Awards <br/> that Vested <br/> During <br/> Year for <br/> Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Fair Value at <br/> Last Day of <br/> Prior Year of <br/> Equity <br/> Awards <br/> Failed to <br/> Meet Vesting <br/> Conditions <br/> During Year <br/> for Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Dollar Value <br/> of any <br/> Dividends or <br/> Other <br/> Earnings Paid <br/> on Stock or <br/> Option <br/> Awards <br/> During Year <br/> Prior to the <br/> Vesting Date <br/> that are not <br/> otherwise <br/> included in the <br/> Total <br/> Compensation <br/> During Year <br/> for Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Aggregate <br/> Equity <br/> Awards <br/> Adjustment </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.25pt 0pt 2.167pt 0pt; width:36.74pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:3.715pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">15,818,976</td> <td style="padding:0pt;padding-left:3.715pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">11,071,066</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:15.395pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:9pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-1"> —</span></td> <td style="padding:0pt;padding-left:15.395pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; "> <div style="font-weight:bold;">$</div> </td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;"> <div style="font-weight:bold;"> <span style="font-weight:normal;">5,933,888</span> </div> </td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:13.15pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:9pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-2"> —</span></td> <td style="padding:0pt;padding-left:13.15pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:14.98pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:9pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-3"> —</span></td> <td style="padding:0pt;padding-left:14.98pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">32,823,930</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> </table><table style="width:416pt;height:104.5pt;margin-left:20pt;margin-top:13pt;border-collapse: collapse;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <tr style="line-height:9pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:137.85pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Year </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Average Reported <br/> Summary <br/> Compensation <br/> Table Total for <br/> non-PEO NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">(a) <br/> Average Reported <br/> Value of Equity <br/> Awards for <br/> non-PEO NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">(b) <br/> Average Aggregate <br/> Equity Award <br/> Adjustments for <br/> non-PEO NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Average <br/> Compensation <br/> Actually Paid <br/> to non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.25pt 0pt 1.5pt 0pt; width:137.85pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.555pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">2,806,280</td> <td style="padding:0pt;padding-left:6.555pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:4.89pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:33pt; text-align:right; white-space:nowrap;">(1,853,019<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:4.89pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.145pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">11,131,678</td> <td style="padding:0pt;padding-left:6.145pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">12,084,939</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:137.85pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2024 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.555pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">3,323,681</td> <td style="padding:0pt;padding-left:6.555pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:4.89pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:33pt; text-align:right; white-space:nowrap;">(2,540,813<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:4.89pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.145pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">2,346,845</td> <td style="padding:0pt;padding-left:6.145pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">3,129,713</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:137.85pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2023 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.555pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">2,244,223</td> <td style="padding:0pt;padding-left:6.555pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:4.89pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:33pt; text-align:right; white-space:nowrap;">(1,409,527<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:4.89pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.145pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">3,988,929</td> <td style="padding:0pt;padding-left:6.145pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">4,823,625</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:137.85pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2022 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.555pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">1,763,908</td> <td style="padding:0pt;padding-left:6.555pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:4.89pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:33pt; text-align:right; white-space:nowrap;">(1,179,023<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:4.89pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.145pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">1,592,825</td> <td style="padding:0pt;padding-left:6.145pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">2,177,710</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> </table><div style="margin-left: 0pt; width: 108pt; margin-top: 0pt; font-size: 1pt; line-height: 0pt; border-bottom: 1pt solid #000000; ">​</div><div style="margin-left:20pt; margin-top:6pt; text-align:justify; width:436pt; line-height:12pt;font-weight:normal;font-size:10pt;"> <span style=" position:relative; bottom:4.25pt;font-size:7.5pt;letter-spacing:0.15pt;">(a)</span><span style="letter-spacing:0.2pt;">   Represents the reported value of equity awards as reported in the “Stock Awards” and “Option Awards” columns in the Summary Compensation Table for the applicable year. </span> </div><div style="margin-left:20pt; text-align:justify; width:436pt; line-height:9.5pt;font-weight:normal;font-size:10pt;"> <span style=" position:relative; bottom:4.25pt;font-size:7.5pt;letter-spacing:0.15pt;">(b)</span><span style="letter-spacing:0.2pt;">   The amounts deducted or added in calculating the equity award adjustments are as follows: </span> </div><table style="width:416pt;height:230.5pt;margin-left:20pt;margin-top:10pt;border-collapse: collapse;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <tr style="line-height:9pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:47.3pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Year </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Year-End <br/> Fair <br/> Value of <br/> Equity <br/> Awards <br/> Granted <br/> During <br/> Year That <br/> Remained <br/> Unvested as of <br/> Last Day of <br/> Year for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Change in <br/> Fair <br/> Value <br/> from Last <br/> Day of Prior <br/> Year to <br/> Last Day <br/> of Year of <br/> Unvested Equity <br/> Awards for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Vesting-Date <br/> Fair Value of <br/> Equity Awards <br/> Granted During <br/> Year that <br/> Vested During <br/> Year for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Change in <br/> Fair Value <br/> from <br/> Last Day <br/> of Prior Year <br/> to Vesting <br/> Date of <br/> Unvested <br/> Equity <br/> Awards that <br/> Vested <br/> During <br/> Year for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Fair Value <br/> at Last <br/> Day of <br/> Prior Year <br/> of Equity <br/> Awards <br/> Failed to <br/> Meet <br/> Vesting <br/> Conditions <br/> During <br/> Year for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Dollar <br/> Value of <br/> any <br/> Dividends <br/> or Other <br/> Earnings <br/> Paid on <br/> Stock or <br/> Option <br/> Awards <br/> During <br/> Year Prior <br/> to the <br/> Vesting <br/> Date that <br/> are not <br/> otherwise <br/> included in <br/> the Total <br/> Compensation <br/> During <br/> Year for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Average <br/> Aggregate <br/> Equity <br/> Awards <br/> Adjustment </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.25pt 0pt 2.167pt 0pt; width:47.3pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:1.205pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">6,153,861</td> <td style="padding:0pt;padding-left:1.205pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:4.415pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">3,941,821</td> <td style="padding:0pt;padding-left:4.415pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:18.83pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:7.5pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-4">—</span></td> <td style="padding:0pt;padding-left:18.83pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; "> <div style="font-weight:bold;">$</div> </td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;"> <div style="font-weight:bold;"> <span style="font-weight:normal;">1,035,996</span> </div> </td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:10.415pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:7.5pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-5">—</span></td> <td style="padding:0pt;padding-left:10.415pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:16.165pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:7.5pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-6">—</span></td> <td style="padding:0pt;padding-left:16.165pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">11,131,678</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> </table><div style="margin-top:2pt; text-align:justify; width:456pt; line-height:12pt;font-weight:normal;font-size:10pt;"> <span style=" position:relative; bottom:4.25pt;font-size:7.5pt;letter-spacing:0.15pt;">(3)</span><span style="letter-spacing:0.2pt;">   For the relevant fiscal year, represents the cumulative TSR of our common stock and our Peer Group at the end of each fiscal year. In each case, assume an initial investment of $100 on December 31, 2022. The Peer Group reflects the Nasdaq Biotechnology Index, which is the same industry peer group used in the stock performance graph required by Item 201(e) of Regulation S-K and included in our Annual Report. </span> </div> Revenue 7712736 34945674 2806280 12084939 708.21 120.69 -68924000 158320000 6751230 6236714 3323681 3129713 241.48 91.15 -130394000 13996000 4889498 15455856 2244223 4823625 247.02 92.42 -78502000 17488000 10762132 13888510 1763908 2177710 130.8 89.09 -41015000 15935000 <div style="margin-top:6pt; text-align:justify; width:456pt; line-height:12pt;"> <span style=" position:relative; bottom:4.25pt;font-size:7.5pt;letter-spacing:0.15pt;">(1)</span><span style="letter-spacing:0.2pt;">   For each fiscal year, represents amount reported for our PEO and average amount reported for our NEOs, in each case in the Total column of the Summary of Compensation Table. Our PEO and NEOs for each of these fiscal years are shown below: </span> </div><table style="width:416pt;height:65.5pt;margin-left:20pt;margin-top:10pt;border-collapse: collapse;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <tr style="line-height:8pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.5pt 0pt; width:145.28pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Year </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.5pt 0pt; width:88.7pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:-0.16pt;">PEO </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.5pt 0pt; width:158.02pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:-0.16pt;">Non-PEO NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;">​</td> </tr> <tr style="line-height:12pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:top;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:1.917pt 0pt 0.5pt 0pt; width:145.28pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:1.917pt 0pt 0.5pt 0pt; width:88.7pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:0.2pt;">Roger A. Jeffs, Ph.D. </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:1.917pt 0pt 0.5pt 0pt; width:158.02pt;"> <div style="text-align:center;"> <span style="letter-spacing:0.2pt;">Michael Kaseta, Russell Schundler, <br/> Rajeev Saggar, M.D., Scott Moomaw </span> </div> </td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;white-space:nowrap;text-align:center;vertical-align:top;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 0.5pt 0pt; width:145.28pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2024 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:3.5pt 0pt 0.5pt 0pt; width:88.7pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:0.2pt;">Roger A. Jeffs, Ph.D. </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:3.5pt 0pt 0.5pt 0pt; width:158.02pt;"> <div style="text-align:center;"> <span style="letter-spacing:0.2pt;">Michael Kaseta, Russell Schundler </span> </div> </td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:top;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 0.5pt 0pt; width:145.28pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2023 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:3.5pt 0pt 0.5pt 0pt; width:88.7pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:0.2pt;">Roger A. Jeffs, Ph.D. </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:3.5pt 0pt 0.5pt 0pt; width:158.02pt;"> <div style="text-align:center;"> <span style="letter-spacing:0.2pt;">Michael Kaseta, Russell Schundler </span> </div> </td> <td style="padding:0pt; width:0pt;">​</td> </tr> </table><table style="width:416pt;height:23.5pt;margin-left:20pt;margin-top:0pt;border-collapse: collapse;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <tr style="line-height:8pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.5pt 0pt; width:145.28pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Year </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.5pt 0pt; width:88.7pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:-0.16pt;">PEO </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.5pt 0pt; width:158.02pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:-0.16pt;">Non-PEO NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:top;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.25pt 0pt 2.5pt 0pt; width:145.28pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2022 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:3.25pt 0pt 2.5pt 0pt; width:88.7pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:0.2pt;">Roger A. Jeffs, Ph.D. </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:3.25pt 0pt 2.5pt 0pt; width:158.02pt;"> <div style="text-align:center;"> <span style="letter-spacing:0.2pt;">Michael Kaseta, Russell Schundler</span> </div> </td> <td style="padding:0pt; width:0pt;">​</td> </tr> </table> Roger A. Jeffs, Ph.D <div style="margin-top:10pt; text-align:justify; width:456pt; line-height:12pt;font-weight:normal;font-size:10pt;"> <span style=" position:relative; bottom:4.25pt;font-size:7.5pt;letter-spacing:0.15pt;">(2)</span><span style="letter-spacing:0.2pt;">   Amounts represent Compensation Actually Paid to our PEO and the average Compensation Actually Paid to our non-PEO NEOs for the relevant fiscal year. Compensation Actually Paid represents the amount reported in the Total column of the Summary Compensation Table for the applicable fiscal year, adjusted as shown below. Fair value or change in fair value, as applicable, of equity awards in the Compensation Actually Paid columns was determined as follows: (i) the fair value as of the end of the fiscal year of outstanding and unvested equity awards granted in that year; (ii) the change in fair value during the year of equity awards granted in prior years that remained outstanding and unvested at the end of the year; (iii) the fair value as of the vesting date of equity awards that were granted and vested in that year; and (iv) the change in fair value during the year through the vesting date of equity awards granted in prior years that vested during that year. Equity values are calculated in accordance with ASC Topic 718. </span> </div><table style="width:416pt;height:104.5pt;margin-left:20pt;margin-top:13pt;border-collapse: collapse;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <tr style="line-height:9pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:137.85pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Year </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Average Reported <br/> Summary <br/> Compensation <br/> Table Total for <br/> non-PEO NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">(a) <br/> Average Reported <br/> Value of Equity <br/> Awards for <br/> non-PEO NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">(b) <br/> Average Aggregate <br/> Equity Award <br/> Adjustments for <br/> non-PEO NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Average <br/> Compensation <br/> Actually Paid <br/> to non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.25pt 0pt 1.5pt 0pt; width:137.85pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.555pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">2,806,280</td> <td style="padding:0pt;padding-left:6.555pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:4.89pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:33pt; text-align:right; white-space:nowrap;">(1,853,019<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:4.89pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.145pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">11,131,678</td> <td style="padding:0pt;padding-left:6.145pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">12,084,939</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:137.85pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2024 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.555pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">3,323,681</td> <td style="padding:0pt;padding-left:6.555pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:4.89pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:33pt; text-align:right; white-space:nowrap;">(2,540,813<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:4.89pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.145pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">2,346,845</td> <td style="padding:0pt;padding-left:6.145pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">3,129,713</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:137.85pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2023 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.555pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">2,244,223</td> <td style="padding:0pt;padding-left:6.555pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:4.89pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:33pt; text-align:right; white-space:nowrap;">(1,409,527<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:4.89pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.145pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">3,988,929</td> <td style="padding:0pt;padding-left:6.145pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">4,823,625</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:137.85pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2022 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.555pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">1,763,908</td> <td style="padding:0pt;padding-left:6.555pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:4.89pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:33pt; text-align:right; white-space:nowrap;">(1,179,023<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:4.89pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.145pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">1,592,825</td> <td style="padding:0pt;padding-left:6.145pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">2,177,710</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> </table><div style="margin-left: 0pt; width: 108pt; margin-top: 0pt; font-size: 1pt; line-height: 0pt; border-bottom: 1pt solid #000000; ">​</div><div style="margin-left:20pt; margin-top:6pt; text-align:justify; width:436pt; line-height:12pt;font-weight:normal;font-size:10pt;"> <span style=" position:relative; bottom:4.25pt;font-size:7.5pt;letter-spacing:0.15pt;">(a)</span><span style="letter-spacing:0.2pt;">   Represents the reported value of equity awards as reported in the “Stock Awards” and “Option Awards” columns in the Summary Compensation Table for the applicable year. </span> </div><div style="margin-left:20pt; text-align:justify; width:436pt; line-height:9.5pt;font-weight:normal;font-size:10pt;"> <span style=" position:relative; bottom:4.25pt;font-size:7.5pt;letter-spacing:0.15pt;">(b)</span><span style="letter-spacing:0.2pt;">   The amounts deducted or added in calculating the equity award adjustments are as follows: </span> </div><table style="width:416pt;height:230.5pt;margin-left:20pt;margin-top:10pt;border-collapse: collapse;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <tr style="line-height:9pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:47.3pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Year </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Year-End <br/> Fair <br/> Value of <br/> Equity <br/> Awards <br/> Granted <br/> During <br/> Year That <br/> Remained <br/> Unvested as of <br/> Last Day of <br/> Year for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Change in <br/> Fair <br/> Value <br/> from Last <br/> Day of Prior <br/> Year to <br/> Last Day <br/> of Year of <br/> Unvested Equity <br/> Awards for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Vesting-Date <br/> Fair Value of <br/> Equity Awards <br/> Granted During <br/> Year that <br/> Vested During <br/> Year for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Change in <br/> Fair Value <br/> from <br/> Last Day <br/> of Prior Year <br/> to Vesting <br/> Date of <br/> Unvested <br/> Equity <br/> Awards that <br/> Vested <br/> During <br/> Year for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Fair Value <br/> at Last <br/> Day of <br/> Prior Year <br/> of Equity <br/> Awards <br/> Failed to <br/> Meet <br/> Vesting <br/> Conditions <br/> During <br/> Year for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Dollar <br/> Value of <br/> any <br/> Dividends <br/> or Other <br/> Earnings <br/> Paid on <br/> Stock or <br/> Option <br/> Awards <br/> During <br/> Year Prior <br/> to the <br/> Vesting <br/> Date that <br/> are not <br/> otherwise <br/> included in <br/> the Total <br/> Compensation <br/> During <br/> Year for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Average <br/> Aggregate <br/> Equity <br/> Awards <br/> Adjustment </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.25pt 0pt 2.167pt 0pt; width:47.3pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:1.205pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">6,153,861</td> <td style="padding:0pt;padding-left:1.205pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:4.415pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">3,941,821</td> <td style="padding:0pt;padding-left:4.415pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:18.83pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:7.5pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-4">—</span></td> <td style="padding:0pt;padding-left:18.83pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; "> <div style="font-weight:bold;">$</div> </td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;"> <div style="font-weight:bold;"> <span style="font-weight:normal;">1,035,996</span> </div> </td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:10.415pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:7.5pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-5">—</span></td> <td style="padding:0pt;padding-left:10.415pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:16.165pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:7.5pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-6">—</span></td> <td style="padding:0pt;padding-left:16.165pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">11,131,678</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> </table> <div style="margin-top:10pt; text-align:justify; width:456pt; line-height:12pt;font-weight:normal;font-size:10pt;"> <span style=" position:relative; bottom:4.25pt;font-size:7.5pt;letter-spacing:0.15pt;">(2)</span><span style="letter-spacing:0.2pt;">   Amounts represent Compensation Actually Paid to our PEO and the average Compensation Actually Paid to our non-PEO NEOs for the relevant fiscal year. Compensation Actually Paid represents the amount reported in the Total column of the Summary Compensation Table for the applicable fiscal year, adjusted as shown below. Fair value or change in fair value, as applicable, of equity awards in the Compensation Actually Paid columns was determined as follows: (i) the fair value as of the end of the fiscal year of outstanding and unvested equity awards granted in that year; (ii) the change in fair value during the year of equity awards granted in prior years that remained outstanding and unvested at the end of the year; (iii) the fair value as of the vesting date of equity awards that were granted and vested in that year; and (iv) the change in fair value during the year through the vesting date of equity awards granted in prior years that vested during that year. Equity values are calculated in accordance with ASC Topic 718. </span> </div><table style="width:416pt;height:95.5pt;margin-left:20pt;margin-top:10pt;border-collapse: collapse;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <tr style="line-height:9pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:121.41pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Year </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Reported Summary <br/> Compensation Table <br/> Total for Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">(a) <br/> Reported Value of <br/> Equity Awards for <br/> Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">(b) <br/> Aggregate Equity <br/> Award Adjustments <br/> for Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:6pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Compensation <br/> Actually Paid to <br/> Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.25pt 0pt 1.5pt 0pt; width:121.41pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:8.765pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">7,712,736</td> <td style="padding:0pt;padding-left:8.765pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:3.165pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:36.75pt; text-align:right; white-space:nowrap;">(5,590,992<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:3.165pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.96pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">32,823,930</td> <td style="padding:0pt;padding-left:6.96pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:1.92pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; "> <div style="font-weight:bold;">$</div> </td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;"> <div style="font-weight:bold;"> <span style="font-weight:normal;">34,945,674</span> </div> </td> <td style="padding:0pt;padding-left:1.92pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:121.41pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2024 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:8.765pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">6,751,230</td> <td style="padding:0pt;padding-left:8.765pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:3.165pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:36.75pt; text-align:right; white-space:nowrap;">(5,533,450<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:3.165pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.96pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">5,018,934</td> <td style="padding:0pt;padding-left:6.96pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:1.92pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; "> <div style="font-weight:bold;">$</div> </td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;"> <div style="font-weight:bold;"> <span style="font-weight:normal;">6,236,714</span> </div> </td> <td style="padding:0pt;padding-left:1.92pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:121.41pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2023 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:8.765pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">4,889,498</td> <td style="padding:0pt;padding-left:8.765pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:3.165pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:36.75pt; text-align:right; white-space:nowrap;">(3,566,418<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:3.165pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.96pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">14,132,776</td> <td style="padding:0pt;padding-left:6.96pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:1.92pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; "> <div style="font-weight:bold;">$</div> </td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;"> <div style="font-weight:bold;"> <span style="font-weight:normal;">15,455,856</span> </div> </td> <td style="padding:0pt;padding-left:1.92pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> <tr style="line-height:10pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:121.41pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2022 </span> </div> </td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:8.765pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">10,762,132</td> <td style="padding:0pt;padding-left:8.765pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:3.165pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:36.75pt; text-align:right; white-space:nowrap;">(10,229,906<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:3.165pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:6.96pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">13,356,284</td> <td style="padding:0pt;padding-left:6.96pt;width:0pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt; width:6pt;">​</td> <td style="padding:0pt;padding-left:1.92pt;width:0pt;">​</td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:3.75pt; text-align:right; "> <div style="font-weight:bold;">$</div> </td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;"> <div style="font-weight:bold;"> <span style="font-weight:normal;">13,888,510</span> </div> </td> <td style="padding:0pt;padding-left:1.92pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> </table><div style="margin-left: 0pt; width: 108pt; margin-top: 0pt; font-size: 1pt; line-height: 0pt; border-bottom: 1pt solid #000000; ">​</div><div style="margin-left:20pt; margin-top:6pt; text-align:justify; width:436pt; line-height:12pt;font-weight:normal;font-size:10pt;"> <span style=" position:relative; bottom:4.25pt;font-size:7.5pt;letter-spacing:0.15pt;">(a)</span><span style="letter-spacing:0.2pt;">   Represents the reported value of equity awards as reported in the “Stock Awards” and “Option Awards” columns in the Summary Compensation Table for the applicable year. </span> </div><div style="margin-left:20pt; margin-top:6pt; text-align:justify; width:436pt; line-height:9.5pt;font-weight:normal;font-size:10pt;"> <span style=" position:relative; bottom:4.25pt;font-size:7.5pt;letter-spacing:0.15pt;">(b)</span><span style="letter-spacing:0.2pt;">   The amounts deducted or added in calculating the equity award adjustments are as follows: </span> </div><table style="width:416pt;height:176.5pt;margin-left:20pt;margin-top:10pt;border-collapse: collapse;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <tr style="line-height:9pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:36.74pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Year </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Year-End Fair <br/> Value of Equity <br/> Awards Granted <br/> During Year <br/> That <br/> Remained <br/> Unvested as of <br/> Last Day of Year <br/> for Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Change in <br/> Fair Value <br/> from Last <br/> Day of Prior <br/> Year to Last <br/> Day of Year <br/> of Unvested <br/> Equity <br/> Awards for <br/> Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Vesting-Date <br/> Fair Value of <br/> Equity Awards <br/> Granted <br/> During Year <br/> that Vested <br/> During Year <br/> for Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Change in <br/> Fair Value <br/> from Last <br/> Day of <br/> Prior Year <br/> to Vesting <br/> Date of <br/> Unvested <br/> Equity <br/> Awards <br/> that Vested <br/> During <br/> Year for <br/> Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Fair Value at <br/> Last Day of <br/> Prior Year of <br/> Equity <br/> Awards <br/> Failed to <br/> Meet Vesting <br/> Conditions <br/> During Year <br/> for Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Dollar Value <br/> of any <br/> Dividends or <br/> Other <br/> Earnings Paid <br/> on Stock or <br/> Option <br/> Awards <br/> During Year <br/> Prior to the <br/> Vesting Date <br/> that are not <br/> otherwise <br/> included in the <br/> Total <br/> Compensation <br/> During Year <br/> for Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Aggregate <br/> Equity <br/> Awards <br/> Adjustment </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.25pt 0pt 2.167pt 0pt; width:36.74pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:3.715pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">15,818,976</td> <td style="padding:0pt;padding-left:3.715pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">11,071,066</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:15.395pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:9pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-1"> —</span></td> <td style="padding:0pt;padding-left:15.395pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; "> <div style="font-weight:bold;">$</div> </td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;"> <div style="font-weight:bold;"> <span style="font-weight:normal;">5,933,888</span> </div> </td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:13.15pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:9pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-2"> —</span></td> <td style="padding:0pt;padding-left:13.15pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:14.98pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:9pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-3"> —</span></td> <td style="padding:0pt;padding-left:14.98pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">32,823,930</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> </table> 7712736 -5590992 32823930 34945674 6751230 -5533450 5018934 6236714 4889498 -3566418 14132776 15455856 10762132 -10229906 13356284 13888510 The amounts deducted or added in calculating the equity award adjustments are as follows: <table style="width:416pt;height:176.5pt;margin-left:20pt;margin-top:10pt;border-collapse: collapse;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <tr style="line-height:9pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:36.74pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Year </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Year-End Fair <br/> Value of Equity <br/> Awards Granted <br/> During Year <br/> That <br/> Remained <br/> Unvested as of <br/> Last Day of Year <br/> for Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Change in <br/> Fair Value <br/> from Last <br/> Day of Prior <br/> Year to Last <br/> Day of Year <br/> of Unvested <br/> Equity <br/> Awards for <br/> Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Vesting-Date <br/> Fair Value of <br/> Equity Awards <br/> Granted <br/> During Year <br/> that Vested <br/> During Year <br/> for Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Change in <br/> Fair Value <br/> from Last <br/> Day of <br/> Prior Year <br/> to Vesting <br/> Date of <br/> Unvested <br/> Equity <br/> Awards <br/> that Vested <br/> During <br/> Year for <br/> Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Fair Value at <br/> Last Day of <br/> Prior Year of <br/> Equity <br/> Awards <br/> Failed to <br/> Meet Vesting <br/> Conditions <br/> During Year <br/> for Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Dollar Value <br/> of any <br/> Dividends or <br/> Other <br/> Earnings Paid <br/> on Stock or <br/> Option <br/> Awards <br/> During Year <br/> Prior to the <br/> Vesting Date <br/> that are not <br/> otherwise <br/> included in the <br/> Total <br/> Compensation <br/> During Year <br/> for Dr. Jeffs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Aggregate <br/> Equity <br/> Awards <br/> Adjustment </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.25pt 0pt 2.167pt 0pt; width:36.74pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:3.715pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">15,818,976</td> <td style="padding:0pt;padding-left:3.715pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">11,071,066</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:15.395pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:9pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-1"> —</span></td> <td style="padding:0pt;padding-left:15.395pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; "> <div style="font-weight:bold;">$</div> </td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;"> <div style="font-weight:bold;"> <span style="font-weight:normal;">5,933,888</span> </div> </td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:13.15pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:9pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-2"> —</span></td> <td style="padding:0pt;padding-left:13.15pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:14.98pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:9pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-3"> —</span></td> <td style="padding:0pt;padding-left:14.98pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">32,823,930</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> </table>The amounts deducted or added in calculating the equity award adjustments are as follows: <table style="width:416pt;height:230.5pt;margin-left:20pt;margin-top:10pt;border-collapse: collapse;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <tr style="line-height:9pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:47.3pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Year </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Year-End <br/> Fair <br/> Value of <br/> Equity <br/> Awards <br/> Granted <br/> During <br/> Year That <br/> Remained <br/> Unvested as of <br/> Last Day of <br/> Year for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Change in <br/> Fair <br/> Value <br/> from Last <br/> Day of Prior <br/> Year to <br/> Last Day <br/> of Year of <br/> Unvested Equity <br/> Awards for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Vesting-Date <br/> Fair Value of <br/> Equity Awards <br/> Granted During <br/> Year that <br/> Vested During <br/> Year for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Change in <br/> Fair Value <br/> from <br/> Last Day <br/> of Prior Year <br/> to Vesting <br/> Date of <br/> Unvested <br/> Equity <br/> Awards that <br/> Vested <br/> During <br/> Year for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Fair Value <br/> at Last <br/> Day of <br/> Prior Year <br/> of Equity <br/> Awards <br/> Failed to <br/> Meet <br/> Vesting <br/> Conditions <br/> During <br/> Year for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Dollar <br/> Value of <br/> any <br/> Dividends <br/> or Other <br/> Earnings <br/> Paid on <br/> Stock or <br/> Option <br/> Awards <br/> During <br/> Year Prior <br/> to the <br/> Vesting <br/> Date that <br/> are not <br/> otherwise <br/> included in <br/> the Total <br/> Compensation <br/> During <br/> Year for <br/> non-PEO <br/> NEOs </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;">​</td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Average <br/> Aggregate <br/> Equity <br/> Awards <br/> Adjustment </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;">​</td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.25pt 0pt 2.167pt 0pt; width:47.3pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:1.205pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">6,153,861</td> <td style="padding:0pt;padding-left:1.205pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:4.415pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;">3,941,821</td> <td style="padding:0pt;padding-left:4.415pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:18.83pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:7.5pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-4">—</span></td> <td style="padding:0pt;padding-left:18.83pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; "> <div style="font-weight:bold;">$</div> </td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:30.75pt; text-align:right; white-space:nowrap;"> <div style="font-weight:bold;"> <span style="font-weight:normal;">1,035,996</span> </div> </td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:10.415pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:7.5pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-5">—</span></td> <td style="padding:0pt;padding-left:10.415pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:16.165pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:7.5pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-6">—</span></td> <td style="padding:0pt;padding-left:16.165pt;width:0pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt; width:2.5pt;">​</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:3.75pt; text-align:right; ">$</td> <td style="padding:3.25pt 0pt 2.167pt 0pt; min-width:34.5pt; text-align:right; white-space:nowrap;">11,131,678</td> <td style="padding:0pt;padding-left:0pt;width:0pt;">​</td> <td style="padding:0pt; width:0pt;">​</td> </tr> </table> 15818976 11071066 5933888 32823930 2806280 -1853019 11131678 12084939 3323681 -2540813 2346845 3129713 2244223 -1409527 3988929 4823625 1763908 -1179023 1592825 2177710 6153861 3941821 1035996 11131678 <div style="margin-top:2pt; text-align:justify; width:456pt; line-height:12pt;font-weight:normal;font-size:10pt;"> <span style=" position:relative; bottom:4.25pt;font-size:7.5pt;letter-spacing:0.15pt;">(3)</span><span style="letter-spacing:0.2pt;">   For the relevant fiscal year, represents the cumulative TSR of our common stock and our Peer Group at the end of each fiscal year. In each case, assume an initial investment of $100 on December 31, 2022. The Peer Group reflects the Nasdaq Biotechnology Index, which is the same industry peer group used in the stock performance graph required by Item 201(e) of Regulation S-K and included in our Annual Report. </span> </div> <img alt="[MISSING IMAGE: bc_comppaidvstsr-4c.jpg]" src="bc_comppaidvstsr-4c.jpg" style="height: 343px; width: 581px;"/> <img alt="[MISSING IMAGE: bc_comppaidvstsr-4c.jpg]" src="bc_comppaidvstsr-4c.jpg" style="height: 343px; width: 581px;"/> <div style="position:relative;margin-top:14.69pt; text-align:center; width:456pt;"> <img alt="[MISSING IMAGE: bc_comppaidvsnetloss-4c.jpg]" src="bc_comppaidvsnetloss-4c.jpg" style="height: 335px; width: 581px;"/> </div> <img alt="[MISSING IMAGE: bc_comppaidvsrevenue-4c.jpg]" src="bc_comppaidvsrevenue-4c.jpg" style="height: 335px; width: 581px;"/> DEF 14A 0001819576 false