X0609 4 2026-04-22 0 0001374339 ProMIS Neurosciences Inc. PMN 0001927062 Kirwin Patrick D. true C/O PROMIS NEUROSCIENCES INC. SUITE 200, 1920 YONGE STREET TORONTO A6 M4S 3E2 ONTARIO, CANADA 1 0 0 0 0 Common Shares 2026-04-22 4 P 0 4000 11.33 A 4653 I By Patrick D. Kirwin Professional Corp Common Shares 305 I By his spouse Common Shares 5135 D /s/ Max A. Milbury, Attorney in Fact for Patrick Kirwin 2026-04-23