X0609 4 2026-04-23 0001889109 BELITE BIO, INC BLTE 0002013987 MATA NATHAN L. false 7708 MARKER ROAD SAN DIEGO CA 92130 false true false false Chief Scientific Officer true American depositary share 2026-04-23 4 S false 267 164.4734 D 10399 D American depositary share 2026-04-23 4 S false 158 165.3759 D 10241 D American depositary share 2026-04-23 4 S false 127 166.5609 D 10114 D American depositary share 2026-04-23 4 S false 373 167.3743 D 9741 D American depositary share 2026-04-23 4 S false 54 168.4339 D 9687 D American depositary share 2026-04-23 4 S false 21 169.5567 D 9666 D Each American depositary share represents one ordinary share, par value US$0.0001 per share, of the issuer. The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on 12/10/2025. Represents the weighted average price of shares sold at prices that ranged from $164.03 to $164.99. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares sold at each separate price. Represents the weighted average price of shares sold at prices that ranged from $165.02 to $165.915. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares sold at each separate price. Represents the weighted average price of shares sold at prices that ranged from $166 to $166.9. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares sold at each separate price. Represents the weighted average price of shares sold at prices that ranged from $167.01 to $167.92. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares sold at each separate price. Represents the weighted average price of shares sold at prices that ranged from $168.15 to $168.92. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares sold at each separate price. Represents the weighted average price of shares sold at prices that ranged from $169.55 to $169.69. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares sold at each separate price. /s/ Nathan L. Mata 2026-04-24