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      <liveTestFlag>LIVE</liveTestFlag>
      <filer>
        <issuerCredentials>
          <cik>0002038166</cik>
          <ccc>XXXXXXXX</ccc>
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      <flags>
        <shellCompanyFlag>N</shellCompanyFlag>
        <successorFilingFlag>N</successorFilingFlag>
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      <reportingPeriod>12-31-2025</reportingPeriod>
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    <item1>
      <formIndication>Annual Report</formIndication>
      <fiscalYearEnd>12-31-2025</fiscalYearEnd>
      <street1>2009 Mackenzie Way</street1>
      <street2>Suite 100</street2>
      <city>Cranberry Twp</city>
      <stateOrCountry>PA</stateOrCountry>
      <zipCode>16066</zipCode>
      <phoneNumber>888-691-5839</phoneNumber>
      <issuedSecuritiesTitle>Class A Common</issuedSecuritiesTitle>
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    <item1Info>
      <issuerName>NOK Therapeutics, Inc.</issuerName>
      <cik>0002038166</cik>
      <jurisdictionOrganization>FL</jurisdictionOrganization>
      <irsNum>99-3344253</irsNum>
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