X0609 4 2026-04-20 1 0002096997 Kailera Therapeutics, Inc. KLRA 0001493215 RTW INVESTMENTS, LP false 40 10TH AVENUE, FLOOR 7 NEW YORK NY 10014 false false true false 0001493280 WONG RODERICK false C/O RTW INVESTMENTS, LP 40 10TH AVENUE, FLOOR 7 NEW YORK NY 10014 0 0 1 0 0 Common Stock 2026-04-20 4 C 0 10276820 A 10276820 I See footnote Common Stock 2026-04-20 4 P 0 500000 16 A 10776820 I See footnote Series A Preferred Stock 2026-04-20 4 C 0 8250000 D Common Stock 8250000 0 I See footnote Series B Preferred Stock 2026-04-20 4 C 0 2026820 D Common Stock 2026820 0 I See footnote Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into shares of Common Stock immediately prior to the closing of the Issuer's initial public offering for no additional consideration on a 1-for-1 basis and had no expiration date. Held by certain affiliated funds managed by RTW Investments, LP ("RTW"). Roderick Wong, M.D. serves as the Managing Partner and Chief Investment Officer of RTW. The Reporting Persons disclaim beneficial ownership of the reported securities for purposes of Section 16 under the Securities Exchange Act of 1934, as amended, except to the extent of their pecuniary interest therein. /s/ Roderick Wong, for RTW Investments, LP, By: Roderick Wong, M.D., Managing Partner 2026-04-22 /s/ Roderick Wong, By: Roderick Wong, M.D. 2026-04-22