Statement of Additional Information Supplement

April 30, 2026

Morgan Stanley Institutional Fund Trust

Supplement dated April 30, 2026 to the Morgan Stanley Institutional Fund Trust Statement of Additional Information dated January 28, 2026

Discovery Portfolio

Corporate Bond Portfolio

Global Strategist Portfolio

Ultra-Short Income Portfolio

Effective immediately, the table in the section of the Statement of Additional Information entitled "Disclosure of Portfolio Holdings" is hereby deleted and replaced with the following:

Name				Frequency1​				Lag Time
Service Providers
State Street Bank and Trust Company				Daily basis				Daily
BlackRock Financial Management Inc.2​				Daily basis				3​
KellyCo Marketing				As needed				Varying lag times after the date of the information
Financial Recovery Technologies				Daily basis				Daily
Commcise Software Limited4​				Monthly basis				Approximately three business days
Virtu Financial, Inc.4​				Monthly basis				Approximately three business days
Toppan Merrill5​				Semi-Annual basis				Approximately 15 business days after month end
Fund Rating Agencies
Refinitiv Lipper				Monthly basis				Approximately six business days after month end
Portfolio Analytics Providers
Bloomberg Finance, L.P.				Daily basis				Daily
FactSet Research Systems, Inc.				Daily basis				Daily
BestX Ltd.				Daily basis				Daily
Abel Noser Solutions, LLC				Daily basis				Daily
MSCI Inc.4​				Daily basis				Daily

1  Dissemination of portfolio holdings information to entities listed above may occur less frequently than indicated (or not at all).

2  With respect to the Corporate Bond, Global Strategist and Ultra-Short Income Portfolios, only.

3  Information will typically be provided on a real time basis or as soon thereafter as possible.

4  With respect to the Discovery and Global Strategist Portfolios, only.

5  With respect to the Discovery Portfolio, only.

Please retain this supplement for future reference.