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0.415328920994 Long EC CORP DE N 1 N N N ENLIVEN THERAPEUTICS INC N/A ENLIVEN THERAPEUTICS INC 29337E102 17123.00000000 NS USD 508381.87000000 0.834277511292 Long EC CORP US N 1 N N N LEGEND BIOTECH CORP 254900EIUFZTW136H859 LEGEND BIOTECH CORP SPON ADR 52490G102 55400.00000000 NS USD 1052600.00000000 1.727363936850 Long EC CORP KY N 1 N N N VAXCYTE INC 254900M7NMHTGASX8D95 VAXCYTE INC 92243G108 22513.00000000 NS USD 1389952.62000000 2.280974757475 Long EC CORP US N 1 N N N DISC MEDICINE INC N/A DISC MEDICINE INC 254604101 11078.00000000 NS USD 738016.36000000 1.211118036357 Long EC CORP US N 1 N N N KYMERA THERAPEUTICS INC N/A KYMERA THERAPEUTICS INC 501575104 10000.00000000 NS USD 913500.00000000 1.499094581334 Long EC CORP US N 1 N N OUTSET MEDICAL INC N/A OUTSET MEDICAL INC 690145206 34000.00000000 NS USD 118660.00000000 0.194726396301 Long EC CORP US N 1 N N N OLEMA PHARMACEUTICALS INC N/A OLEMA PHARMACEUTICALS INC 68062P106 18000.00000000 NS USD 435600.00000000 0.714839189523 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392480.00000000 0.644077330358 Long EC CORP US N 1 N N N JANUX THERAPEUTICS INC N/A JANUX THERAPEUTICS INC 47103J105 18809.00000000 NS USD 255990.49000000 0.420091906329 Long EC CORP US N 1 N N N NUVALENT INC N/A NUVALENT INC-A 670703107 6000.00000000 NS USD 611700.00000000 1.003827208979 Long EC CORP US N 1 N N N AMYLYX PHARMACEUTICALS INC N/A AMYLYX PHARMACEUTICALS INC 03237H101 23554.00000000 NS USD 357314.18000000 0.586368638283 Long EC CORP US N 1 N N N NEWAMSTERDAM PHARMA COMPANY NV 984500B6549TF6E14D36 NEWAMSTERDAM PHARMA COMPANY NV N/A 10794.00000000 NS USD 382755.24000000 0.628118561862 Long EC CORP NL N 1 N N STRUCTURE THERAPEUTICS INC N/A STRUCTURE THERAPEUTICS INC ADR 86366E106 7402.00000000 NS USD 466177.96000000 0.765018997015 Long EC CORP KY N 1 N N N WAYSTAR HOLDING CORP 529900QJLKXDYU36MH89 WAYSTAR HOLDING CORP 946784105 60000.00000000 NS USD 1539000.00000000 2.525568210918 Long EC CORP US N 1 N N ZENAS BIOPHARMA INC N/A ZENAS BIOPHARMA INC 98937L105 10000.00000000 NS USD 263500.00000000 0.432415349952 Long EC CORP US N 1 N N N UPSTREAM BIO INC N/A UPSTREAM BIO INC 91678A107 16000.00000000 NS USD 122880.00000000 0.201651606080 Long EC CORP US N 1 N N N KESTRA MEDICAL TECHNOLOGIES INC N/A KESTRA MEDICAL TECHNOLOGIES INC N/A 18400.00000000 NS USD 428352.00000000 0.702944895570 Long EC CORP BM N 1 N N 2026-03-30 Stacie M. Smith Stacie M. Smith Stacie M. Smith President and Treasurer XXXX NPORT-EX 2 QTLY_6998_20260228.htm 010 - Quarterly Front Cover
Quarterly Holdings Report
for
Fidelity® Disruptive Medicine ETF
February 28, 2026
DRM-NPRT3-0426
1.9907233.102
Common Stocks - 99.3%
 
 
Shares
Value ($)
 
BELGIUM - 4.1%
 
 
 
Health Care - 4.1%
 
 
 
Pharmaceuticals - 4.1%
 
 
 
UCB SA
 
8,299
2,474,079
CANADA - 1.1%
 
 
 
Health Care - 1.1%
 
 
 
Biotechnology - 1.1%
 
 
 
Xenon Pharmaceuticals Inc (a)
 
15,658
676,895
CHINA - 0.8%
 
 
 
Health Care - 0.8%
 
 
 
Biotechnology - 0.8%
 
 
 
Zai Lab Ltd ADR (a)
 
24,439
469,718
DENMARK - 1.5%
 
 
 
Health Care - 1.5%
 
 
 
Biotechnology - 1.5%
 
 
 
Ascendis Pharma A/S ADR (a)
 
3,865
902,478
FRANCE - 2.0%
 
 
 
Health Care - 2.0%
 
 
 
Life Sciences Tools & Services - 2.0%
 
 
 
Sartorius Stedim Biotech
 
5,513
1,192,743
GERMANY - 0.3%
 
 
 
Health Care - 0.3%
 
 
 
Biotechnology - 0.3%
 
 
 
BioNTech SE ADR (a)
 
2,296
253,088
NETHERLANDS - 4.5%
 
 
 
Health Care - 4.5%
 
 
 
Biotechnology - 4.5%
 
 
 
Argenx SE ADR (a)
 
3,053
2,341,407
Newamsterdam Pharma Co NV (a)(b)
 
10,794
382,755
 
 
 
 
TOTAL NETHERLANDS
 
 
2,724,162
SWITZERLAND - 1.4%
 
 
 
Health Care - 1.4%
 
 
 
Life Sciences Tools & Services - 1.4%
 
 
 
Lonza Group AG
 
1,242
866,177
UNITED STATES - 83.6%
 
 
 
Health Care - 83.6%
 
 
 
Biotechnology - 33.3%
 
 
 
Alnylam Pharmaceuticals Inc (a)
 
6,060
2,017,495
Caris Life Sciences Inc (a)(b)
 
40,000
805,600
Centessa Pharmaceuticals PLC ADR (a)
 
22,800
612,408
Cogent Biosciences Inc (a)
 
60,000
2,331,001
Cytokinetics Inc (a)(b)
 
13,223
822,735
CytomX Therapeutics Inc (a)(b)
 
112,069
601,811
Disc Medicine Inc (a)
 
11,078
738,016
Insmed Inc (a)
 
8,000
1,194,640
Janux Therapeutics Inc (a)
 
18,809
255,990
Kiniksa Pharmaceuticals International Plc Class A (a)
 
12,000
533,880
Kymera Therapeutics Inc (a)(b)
 
10,000
913,500
Legend Biotech Corp ADR (a)
 
55,400
1,052,600
Mirum Pharmaceuticals Inc (a)
 
3,500
323,015
Moderna Inc (a)(b)
 
29,259
1,567,405
Natera Inc (a)
 
4,179
869,399
Nuvalent Inc Class A (a)
 
6,000
611,700
Olema Pharmaceuticals Inc (a)
 
18,000
435,600
Roivant Sciences Ltd (a)
 
18,000
520,920
Soleno Therapeutics Inc (a)
 
6,105
238,522
Stoke Therapeutics Inc (a)
 
25,079
913,126
Upstream Bio Inc (a)
 
16,000
122,880
Vaxcyte Inc (a)
 
22,513
1,389,953
Veracyte Inc (a)(b)
 
20,000
731,800
Viking Therapeutics Inc (a)
 
13,375
452,610
Zenas Biopharma Inc (a)
 
10,000
263,500
 
 
 
20,320,106
Health Care Equipment & Supplies - 21.1%
 
 
 
Align Technology Inc (a)
 
2,979
566,308
Boston Scientific Corp (a)
 
32,000
2,459,200
Dexcom Inc (a)
 
10,449
767,270
Edwards Lifesciences Corp (a)
 
17,421
1,506,394
Insulet Corp (a)
 
6,372
1,571,399
Intuitive Surgical Inc (a)
 
3,800
1,913,338
iRhythm Technologies Inc (a)
 
3,155
421,981
Kestra Medical Technologies Ltd (a)(b)
 
18,400
428,352
Outset Medical Inc (a)
 
34,000
118,660
Penumbra Inc (a)
 
3,000
1,033,170
PROCEPT BioRobotics Corp (a)(b)
 
10,651
241,671
ResMed Inc
 
2,800
717,528
Stryker Corp
 
2,925
1,133,321
 
 
 
12,878,592
Health Care Providers & Services - 7.5%
 
 
 
Alignment Healthcare Inc (a)
 
30,094
578,407
Guardant Health Inc (a)
 
6,000
563,399
LifeStance Health Group Inc (a)(b)
 
206,792
1,497,174
Privia Health Group Inc (a)
 
45,000
1,068,750
UnitedHealth Group Inc
 
2,973
871,892
 
 
 
4,579,622
Health Care Technology - 6.2%
 
 
 
Doximity Inc Class A (a)
 
16,000
392,480
Veeva Systems Inc Class A (a)
 
10,000
1,820,100
Waystar Holding Corp (a)(b)
 
60,000
1,539,000
 
 
 
3,751,580
Life Sciences Tools & Services - 9.3%
 
 
 
10X Genomics Inc Class A (a)
 
45,000
1,037,250
Bio-Techne Corp
 
8,359
493,181
Danaher Corp
 
12,280
2,586,659
Repligen Corp (a)
 
3,970
511,058
Thermo Fisher Scientific Inc
 
2,036
1,060,980
 
 
 
5,689,128
Pharmaceuticals - 6.2%
 
 
 
Amylyx Pharmaceuticals Inc (a)
 
23,554
357,314
Crinetics Pharmaceuticals Inc (a)(b)
 
19,000
780,900
Eli Lilly & Co
 
1,030
1,083,550
Enliven Therapeutics Inc (a)
 
17,123
508,382
Structure Therapeutics Inc ADR (a)
 
7,402
466,178
WaVe Life Sciences Ltd (a)
 
40,000
557,200
 
 
 
3,753,524
TOTAL UNITED STATES
 
 
50,972,552
 
TOTAL COMMON STOCKS
 (Cost $49,010,378)
 
 
 
60,531,892
 
 
 
 
Money Market Funds - 12.0%
 
 
Yield (%)
Shares
Value ($)
 
Fidelity Cash Central Fund (c)
 
3.70
418,522
418,605
Fidelity Securities Lending Cash Central Fund (c)(d)
 
3.69
6,877,634
6,878,322
 
TOTAL MONEY MARKET FUNDS
 (Cost $7,296,927)
 
 
 
7,296,927
 
 
 
 
 
 
TOTAL INVESTMENT IN SECURITIES - 111.3%
 (Cost $56,307,305)
 
 
 
67,828,819
NET OTHER ASSETS (LIABILITIES) - (11.3)%  
(6,891,931)
NET ASSETS - 100.0%
60,936,888
 
 
Legend
 
(a)
Non-income producing.
 
(b)
Security or a portion of the security is on loan at period end.
 
(c)
Affiliated fund that is generally available only to investment companies and other accounts managed by Fidelity Investments. The rate quoted is the annualized seven-day yield of the fund at period end. A complete unaudited listing of the fund's holdings as of its most recent quarter end is available upon request. In addition, each Fidelity Central Fund's financial statements are available on the SEC's website or upon request.
 
(d)
Investment made with cash collateral received from securities on loan.
 
 
 
 
 
Affiliated Central Funds
 
Fiscal year to date information regarding the Fund's investments in Fidelity Central Funds, including the ownership percentage, is presented below.
Affiliate
Value,
beginning
of period ($)
Purchases ($)
Sales
Proceeds ($)
Dividend
Income ($)
Realized
Gain (loss) ($)
Change in
Unrealized
appreciation
(depreciation) ($)
Value,
end
of period ($)
 
 
Shares,
end
of period
% ownership,
end
of period
Fidelity Cash Central Fund
316,059
5,303,649
5,200,949
10,438
(154)
-
418,605
418,522
0.0%
Fidelity Securities Lending Cash Central Fund
2,691,268
27,596,111
23,408,911
4,339
(146)
-
6,878,322
6,877,634
0.0%
Total
3,007,327
32,899,760
28,609,860
14,777
(300)
-
7,296,927
 
 
 
 
 
 
 
 
 
 
 
 
Amounts in the dividend income column in the above table include any capital gain distributions from underlying funds.
 
Amounts in the dividend income column for Fidelity Securities Lending Cash Central Fund represents the income earned on investing cash collateral, less rebates paid to borrowers and any lending agent fees associated with the loan, plus any premium income received for lending certain types of securities.
Investment Valuation
Investments are valued as of 4:00 p.m. Eastern time on the last calendar day of the period. Securities transactions are accounted for as of trade date. The Board of Trustees (the Board) has designated the Fund's investment adviser as the valuation designee responsible for the fair valuation function and performing fair value determinations as needed. The investment adviser has established a Fair Value Committee (the Committee) to carry out the day-to-day fair valuation responsibilities and has adopted policies and procedures to govern the fair valuation process and the activities of the Committee. In accordance with these fair valuation policies and procedures, which have been approved by the Board, the Fund attempts to obtain prices from one or more third party pricing services or brokers to value its investments. When current market prices, quotations or currency exchange rates are not readily available or reliable, investments will be fair valued in good faith by the Committee, in accordance with the policies and procedures. Factors used in determining fair value vary by investment type and may include market or investment specific events, transaction data, estimated cash flows, and market observations of comparable investments. The frequency that the fair valuation procedures are used cannot be predicted and they may be utilized to a significant extent. The Committee manages the Fund's fair valuation practices and maintains the fair valuation policies and procedures. The Fund's investment adviser reports to the Board information regarding the fair valuation process and related material matters.   
 
The inputs to valuation techniques used to value investments are categorized into a disclosure hierarchy consisting of three levels as shown below:
 
Level 1 - Unadjusted quoted prices in active markets for identical investments
Level 2 - other significant observable inputs (including quoted prices for similar investments, interest rates, prepayment speeds, etc.)
Level 3 - unobservable inputs (including the Fund's own assumptions based on the best information available)
 
Valuation techniques used to value investments by major category are as follows:
Equity securities, including restricted securities, for which market quotations are readily available, are valued at the last reported sale price or official closing price as reported by a third party pricing service on the primary market or exchange on which they are traded and are categorized as Level 1 in the hierarchy. In the event there were no sales during the day or closing prices are not available, securities are valued at the last quoted bid price or may be valued using the last available price and are generally categorized as Level 2 in the hierarchy. For any foreign equity securities, when market or security specific events arise, comparisons to the valuation of American Depositary Receipts (ADRs), futures contracts, Exchange-Traded Funds (ETFs) and certain indexes as well as quoted prices for similar securities may be used and would be categorized as Level 2 in the hierarchy. For equity securities, including restricted securities, where observable inputs are limited, assumptions about market activity and risk are used and these securities may be categorized as Level 3 in the hierarchy.
 
Investments in any open-end mutual funds are valued at their closing net asset value (NAV) each business day and are categorized as Level 1 in the hierarchy.
 
Changes in valuation techniques may result in transfers in or out of an assigned level within the disclosure hierarchy.
 
For additional information on the Fund's significant accounting policies, please refer to the Fund's most recent semiannual or annual shareholder report.
 
The fund's schedule of investments as of the date on the cover of this report has not been audited. This report is provided for the general information of the fund's shareholders. For more information regarding the fund and its holdings, please see the fund's most recent prospectus and annual report.
 
Third party trademarks and service marks are the property of their respective owners. All other trademarks and service marks are the property of FMR LLC or an affiliate.